What risk factors lead to the occurrence of colorectal cancer?

What risk factors lead to colorectal cancer? Colorectal cancer (carcinoma of rectum) is a common malignant tumor in the gastrointestinal tract, and its incidence rate is second only to stomach and esophageal cancer. The early symptoms of colorectal cancer are not very obvious, and many people cannot detect the symptoms of colorectal cancer in time, thus missing the treatment of colorectal cancer. So why do people get colorectal cancer? What factors lead to colorectal cancer?

Factors that may increase the risk of bowel cancer include:

1. Genetic background

Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are both caused by mutations in the corresponding genes. Patients with these diseases not only have a significantly increased risk of developing the disease, but also develop the disease at a younger age.

2. History of inflammatory colitis

Certain colon diseases such as Crohn's disease or ulcerative colitis may increase the risk of colorectal cancer. Their risk of colon cancer is 30 times that of the general population.

3. History of colorectal polyps

Most colorectal cancers develop from small precancerous lesions called polyps. Among them, villous adenomatous polyps are more likely to develop into cancer, with a chance of malignancy of about 25%; tubular adenomatous polyps have a malignancy rate of 1-5%.

4. Age

As age increases, the time that various pathogenic factors stimulate the large intestinal mucosa also increases, and most patients develop the disease after the age of 50.

5. Family history

According to surveys, about 1/4 of colorectal cancer patients have a family history.

Through the above explanation, we know the risk factors that lead to colorectal cancer. I believe everyone has a certain understanding of the causes of colorectal cancer. If you have symptoms of suspected colorectal cancer, you must go to a relevant regular hospital for diagnosis and treatment in time. I hope this article can help you or your friends. This article is for reference only. If you have other questions about colorectal cancer, please consult our experts online.

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