Drinking alcohol is a recognized risk factor for liver cancer in addition to hepatitis B, drinking contaminated water and eating moldy food, but the risk and intrinsic connection have not been clearly identified. Studies have shown that the metabolism of alcohol in the human body is completed through acetaldehyde deoxygenase 2 (ALDH2). The function of acetaldehyde deoxygenase 2 in the human body is to oxidize acetaldehyde into non-carcinogenic acetic acid, and finally decompose it into carbon dioxide and water that are harmless to the human body and excreted from the body. However, when the normal gene of acetaldehyde deoxygenase 2 mutates, the enzyme will lose its activity, causing the acetaldehyde concentration in the blood to increase by more than 6 times after drinking. Long-term alcoholism will accumulate acetaldehyde in the body and may eventually cause liver cells to become cancerous. The study also found that 13% of the Chinese population are carriers of the aldehyde dehydrogenase 2 variant genotype, about 400 to 500 million people, and the vast majority of them are unaware that they are enzyme-deficient. Carriers of "mutated genes" have a 3.51 times higher risk of developing cancer than normal people Experts remind: People who blush or feel nauseous after drinking should be careful There is a large group of carriers of aldehyde deoxygenase 2 gene variants in China, accounting for about 1/3 of the total population. Compared with normal gene carriers of the enzyme, they have no difference in drinking frequency and amount. Those with enzyme deficiency drink a lot. At the same time, 10% of the population in China are carriers of hepatitis B virus, and the potential risk of liver cancer is worrying. At present, aldehyde deoxygenase 2 genotype testing cannot be widely carried out for the general population. How should people reduce the risk of liver cancer from drinking? Studies have found that carriers of the aldehyde deoxygenase 2 gene variant often experience neurological symptoms such as flushing, nausea and tachycardia after drinking. Therefore, if you have the above symptoms after drinking, you should be vigilant, quit drinking or minimize alcohol intake to prevent the occurrence of liver cancer. At the same time, drinking can also cause health damage to normal people, such as alcoholic liver disease and damage to the gastrointestinal mucosa. People should try to drink less or only drink low-alcohol drinks, such as red wine and beer; long-term drinkers should strictly control their alcohol intake to a safe dose of less than 15 grams per day. Liver cancer http://www..com.cn/zhongliu/ga/ |
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