What causes rectal cancer

In recent years, rectal cancer has become one of the major diseases that endanger human health, bringing great pain and distress to mankind. The cause of rectal cancer is still not very clear, but it is generally believed that the following factors have a very important relationship with carcinogenesis.

·Dietary factors High fat, such as meat, high-protein foods, and low-fiber foods, such as starch, potatoes, and carrots, are closely related to the occurrence of colorectal cancer. High-fat diets not only stimulate the increase in bile secretion, but also promote the synthesis of cholesterol and lithocholic acid in the liver, which increases in the intestinal cavity. Under the action of colon bacteria, they are converted into cholesterol metabolites and bile acid, which have carcinogenic effects. Low-fiber foods do not absorb water, reduce the frequency of bowel movements, increase the retention of waste in the intestine, prolong the residence time of feces in the large intestine, and increase the long-term contact between carcinogens and the large intestine mucosa, thus becoming one of the causes of colorectal cancer. Both high fat and low fiber are carcinogens or co-carcinogens, thus increasing the occurrence of colorectal cancer.

Genetic factors are one of the causes of colorectal cancer. In the families of colorectal cancer patients, about 1/4 of new patients have a family history of colorectal cancer. Relatives who have had colorectal cancer are more likely to suffer from the disease than the general population in their lifetime. Cell genetic genes change, resulting in malignant cells with genetic characteristics of the tumor, forming a familial malignancy.

· Rectal polyps Rectal polyps are one of the main factors for the development of rectal cancer. Rectal polyps are the main cause of precancerous lesions, especially familial multiple adenomatous polyposis, which has a higher chance of canceration. The canceration rate of papillary adenomatous polyps is about 25%, and the malignant transformation of tubular adenomatous polyps is also relatively common.

Chronic inflammatory bowel disease Long-term chronic inflammation may be one of the factors causing rectal cancer. Chronic inflammatory stimulation can cause the occurrence of rectal cancer, such as chronic bacterial infection schistosomiasis, amoebic dysentery, chronic nonspecific ulcerative colitis, diverticulitis, chronic bacillary dysentery, etc., which can cause granulomas in the mucosa and can cause cancer through granuloma, inflammatory and pseudopolyp stages.

Data related to cholecystectomy reported that the incidence of intestinal cancer after cholecystectomy is also on the rise. After a long period of extensive clinical practice, it is believed that this is related to the increase in secondary bile acid entering the intestinal cavity.

Others In addition, the occurrence of tumors is also related to environmental factors (climate, work, etc.), mental factors, age, sexually transmitted diseases, endocrine factors, etc., but rectal cancer can only occur under certain conditions.

The above is an introduction to the factors that cause rectal cancer. I hope it will be helpful to everyone. We should start from the little things in our daily lives, develop good living habits, do not ignore every detail in our daily lives, and stay away from viruses. If you have any questions, please consult a doctor.

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