Do you know the main cause of pancreatic cancer?

Do you know the main cause of pancreatic cancer?

The main cause of pancreatic cancer At present, the cause of pancreatic cancer is still unclear, and some environmental factors have been found to be related to the occurrence of pancreatic cancer. The main cause of pancreatic cancer, for a long time, tumor researchers have used epidemiological and laboratory research methods to analyze factors such as age, gender, race, genetics, diet, nutrition, occupation, coffee and tobacco. After extensive research, most people believe that pancreatic cancer is caused by the repeated action of multiple factors. The main cause of pancreatic cancer, high-protein diet may be related to the incidence of pancreatic cancer, which has been confirmed in animal experiments. When mice are fed with soybean meal, the secreted gastrin and cholecystokinin can stimulate pancreatic tissue proliferation and nodule formation. Epidemiological surveys also have evidence to support the above view. For example, smoking, drinking coffee and drinking alcohol can cause increased gastrin secretion, and their role in causing pancreatic cancer needs to be further demonstrated. In recent years, people have been watching the relationship between chronic pancreatitis and pancreatic cancer with great interest. In 1985, Nogueria conducted a study on 136 cases of chronic pancreatitis.

In calcific pancreatitis, 2.2% of cases were found to be accompanied by pancreatic cancer, which is nearly 100 times higher than the incidence of pancreatic cancer in the general population. In a group of autopsy reports on pancreatic cancer, 41% of the pancreatic tissues not involved in the tumor had ductal hyperplasia. Ductal hyperplasia may be caused by the action of carcinogenic factors or endocrine imbalance. Some people used giant voles as experimental subjects and wrapped the pancreatic head with cellophane paper tape. Five days after the operation, epithelial cell hyperplasia and goblet cell metaplasia of the main pancreatic duct in the pancreatic head were found, followed by fibrosis around the pancreatic duct and partial obstruction of the duct. It was proved that pancreatic duct obstruction, retention and pancreatic duct epithelial hyperplasia are closely related to the occurrence of pancreatic cancer.

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