Extraskeletal Ewing sarcoma

Tumors may occur anywhere in the body, and the treatment methods may vary in different parts of the body. Tumors that occur in soft tissue are called extraskeletal Ewing tumors. They usually occur in young and middle-aged people, and are most common in the limbs and other parts of the body. However, it is not very clear from a medical point of view how extraskeletal Ewing tumor is formed, and it may be related to radiation and genetic factors. However, early-stage extraskeletal Ewing tumors are more effectively treated, so the most important thing is to detect them as early as possible.

sarcoma

Extraskeletal Ewing tumor is a tumor that arises in soft tissue and is histologically identical to Ewing tumor of bone. The disease is common in young and middle-aged people, with the limbs and paraspinal soft tissues being the most common sites. The tumor grows rapidly and invasively, is prone to recurrence after surgery, and lung metastasis occurs early. Treatment is mainly surgery, supplemented by chemotherapy and radiotherapy

Causes

The cause of extraskeletal Ewing tumor is still unclear, and may be related to radiation factors, genetic factors, etc.

Clinical manifestations

Extraskeletal Ewing tumor often occurs in young and middle-aged people aged 20 to 30 years old, with similar incidence rates in men and women. The most common sites of occurrence are the limbs and paraspinal soft tissues. The tumor is irregularly nodular or lobed, grows rapidly, is tightly adherent to adjacent tissues, and is soft and brittle. It is easy to relapse after surgical resection and can metastasize early, often to the lungs and bones.

examine

X-ray of extraosseous Ewing tumor shows unclear boundaries of the mass and incomplete capsule. CT examination can be performed if necessary.

diagnosis

The diagnosis can be made based on medical history, clinical manifestations, and imaging examinations. This disease should be differentiated from diseases such as juxtacortical osteosarcoma and periosteal osteosarcoma.

treat

Extraskeletal Ewing tumor grows invasively and is difficult to remove extensively. It is prone to recurrence after surgery and can metastasize to the lungs in the early stages, so it is difficult to control with surgery alone. This disease is sensitive to chemotherapy and radiotherapy, so treatment should be based on chemotherapy and radiotherapy. Once the pathological diagnosis is clear, systemic chemotherapy should be started as soon as possible. Tumors with a diameter of about 10 cm can completely disappear after 1 to 2 chemotherapy sessions. Commonly used chemotherapy drugs include doxorubicin, cyclophosphamide, vincristine, etc. For those who have undergone surgery, in addition to chemotherapy, it is more appropriate to use radiotherapy to the surgical site.