The absolute platelet count is high

As we all know, platelets are actually a kind of coagulant. Whenever there is a wound in our body, platelets can promote blood coagulation and thus reduce blood loss. However, if the platelet count is too high or too low, it may indicate some disease in the body. Next, we will introduce to you the situation where the absolute platelet value is too high, and we hope it will be helpful to you.

If the absolute values ​​of platelets and red blood cells are both high, there is no blood disease and no discomfort symptoms, the first thing to consider is blood concentration. Because these two values ​​are only slightly high, they are not considered to be blood diseases. If you usually drink less water, you can drink more water and check your blood routine again after a while. If it is normal, you don't need to worry about it.

Platelets are small pieces of cytoplasm that detach from the cytoplasm of mature megakaryocytes in the bone marrow . Although megakaryocytes are the smallest in number among the hematopoietic cells in the bone marrow, accounting for only 0.05% of the total number of bone marrow nucleated cells, the platelets they produce are extremely important for the body's hemostatic function. When blood is lost due to vascular trauma, the functional activities of platelets in the physiological hemostasis process can be roughly divided into two stages: the first stage is mainly after the trauma occurs, platelets quickly adhere to the trauma site, aggregate into clusters, and form a relatively soft hemostatic plug; the second stage is mainly to promote blood coagulation and form a solid hemostatic plug.

1. Thrombocytosis : When the platelet count is >400×10^9/L, it is thrombocytosis. Primary thrombocytosis is common in myeloproliferative diseases, such as chronic myeloid leukemia, polycythemia vera, essential thrombocythemia, etc.; thrombocytosis is common in patients with acute and chronic inflammation, iron deficiency anemia and cancer. This type of increase generally does not exceed 500×10^9/L. The situation improves after treatment and the platelet count will quickly drop to normal levels. After splenectomy, platelet count will increase significantly, often higher than 600×10^9/L, and then slowly decrease to the normal range.

2. Thrombocytopenia: When the platelet count is <100×10^9/L, it is thrombocytopenia, which is common in platelet production disorders such as aplastic anemia, acute leukemia, acute radiation sickness, etc.; increased platelet destruction, such as idiopathic thrombocytopenic purpura, hypersplenism, Gaucher disease, etc., excessive consumption such as disseminated intravascular coagulation, familial thrombocytopenia such as giant platelet syndrome, etc.