Many people cannot distinguish between mycoplasma and chlamydia, but no matter which one it is, the disease is more difficult to cause and it is difficult to get a better treatment effect in a short period of time. Sometimes it will cause pneumonia in people. The probability of this happening in children will become greater. It may happen almost all year round, especially in late spring and early autumn. Mycoplasma is a type of minimal prokaryotic cell-type microorganism that has no cell wall, is highly polymorphic, can pass through filters, and can be cultured and proliferated in artificial culture media. Because they can form filamentous and branched shapes, they are called mycoplasmas. Mycoplasmas are widely present in humans and animals. Most of them are non-pathogenic. The mycoplasmas that are pathogenic to humans mainly include Mycoplasma pneumoniae, Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium. Macrophages, IgG and IgM all have certain killing effects on mycoplasma. 1. Mycoplasma pneumoniae Mycoplasma pneumoniae is the pathogen that causes mycoplasma pneumonia, and can also cause upper respiratory tract infections and chronic bronchitis. It is mainly transmitted through the respiratory tract and can occur throughout the year, but is more common in late summer and early autumn. The incidence rate is higher in people aged 1 to 15 years old. The symptoms are mild, including irregular fever, headache, and irritating cough. Sometimes, instead of bronchopneumonia, some patients may develop complications outside the respiratory tract, such as rash, cardiovascular and neurological symptoms. Isolation culture, serological tests, etc. are commonly used in clinical examination. 2. Other Mycoplasmas Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium are pathogens that cause human urogenital tract infections. They are transmitted through sexual contact, causing urogenital tract infections such as urethritis and prostatitis. They can also be transmitted through the placenta, causing premature birth, spontaneous abortion, congenital malformations, stillbirth, and infertility. Infection through the birth canal can cause neonatal pneumonia or meningitis. Gram staining is negative, but it is not easy to stain. It is usually stained with Giemsa and dyed light purple. Mycoplasmas reproduce mainly by binary fission, but can also reproduce by budding, branching into filaments which then break into club-shaped particles. Most mycoplasmas reproduce more slowly than bacteria. The suitable growth temperature is 35°C and the optimum pH is 7.8-8.0. When cultured on solid culture medium, it forms typical "fried egg" shaped colonies. Mycoplasma has weak resistance and is sensitive to heat and dryness, 75% ethanol and coal phenol soap solution, erythromycin, tetracycline, spiramycin, streptomycin, kanamycin and other drugs, but is insensitive to penicillin antibiotics. |
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