What is liver fibrosis

What is liver fibrosis

Liver fibrosis is a disease that occurs in the liver. This disease is relatively rare, but it is still possible. Liver fibrosis can cause us many diseases. There are many reasons for its occurrence, but most people don’t know. Once this disease occurs, you should seek treatment immediately to prevent more serious consequences. So what is liver fibrosis?

Liver fibrosis is a pathophysiological process, which refers to the abnormal proliferation of connective tissue in the liver caused by various pathogenic factors. Any liver damage will lead to liver fibrosis during the process of liver repair and healing. If the damaging factors cannot be removed for a long time, the fibrosis process will continue for a long time and develop into cirrhosis. Therefore it is not an independent disease.

Strictly speaking, liver fibrosis does not have any clinical symptoms. It is mainly caused by various factors that damage the liver, leading to clinical symptoms of hepatitis or further aggravation of liver cirrhosis. The main manifestations are as follows: 1. Fatigue and weakness

2. Loss of appetite

Sometimes accompanied by nausea and vomiting.

3. Chronic indigestion

Abdominal bloating, constipation or diarrhea, dull pain in the liver area, etc. Clinically, some patients have no obvious history of chronic liver disease and are only discovered after further examination.

4. Chronic gastritis

Many patients with chronic hepatitis experience stomach-area symptoms such as acid reflux, belching, hiccups, upper abdominal pain, and upper abdominal fullness.

5. Bleeding

Chronic hepatitis affects the synthesis of prothrombin and other coagulation factors due to decreased liver function. The clinical manifestations of liver fibrosis often include spider angiomas, epistaxis, gingival bleeding, purple spots or bleeding spots on the skin and mucous membranes, and women often have excessive menstruation. The appearance of the above symptoms often indicates that liver fibrosis has developed to the stage of cirrhosis.

The treatment of liver fibrosis mainly includes: removing the pathogenic factors of the primary disease, such as anti-hepatitis B and hepatitis C virus treatment, anti-schistosomiasis treatment, alcohol abstinence, etc. Treatment for liver fibrosis itself, such as by inhibiting inflammation or lipid peroxidation, or inhibiting the proliferation and activation of hepatic stellate cells, and promoting collagen degradation.

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