Anti-Helicobacter pylori triple

In today's hospitals, there are many methods to treat Helicobacter pylori. The two-drug, triple-drug, and quadruple-drug methods are more commonly used. The triple-drug was developed based on the two-drug. It is an antibiotic treatment method that protects the gastric mucosa. Under normal circumstances, the medication will take effect within one to two weeks. So what is the treatment principle of the triple-drug against Helicobacter pylori?

Helicobacter pylori is extremely harmful and is prone to recurrence. So how to eradicate Helicobacter pylori? What are the methods to eradicate Helicobacter pylori?

Triple therapy for Helicobacter pylori

The most commonly used treatment for Helicobacter pylori in clinical practice is triple therapy:

Triple therapy overview:

Triple therapy for gastric cancer refers to a treatment method that includes colloidal bismuth or a proton pump inhibitor (PPI) + two antibiotics. Generally speaking, triple therapy is used for one to two weeks. In addition, gastric mucosal protectants, drugs that promote gastric emptying, anticholine drugs, etc. can be used appropriately according to the condition of the disease.

Advantages of triple therapy:

Compared with single antibiotic therapy and dual therapy, triple therapy has the advantage of high eradication rate. In previous years, when H. pylori resistance was not as common as it is today, the eradication rate of triple therapy could reach 85%-95%.

Problems with triple therapy:

The first is the issue of side effects. Almost all commonly used antibiotics have certain side effects. For example, metronidazole, the two most commonly used antibiotics in the triple therapy, can cause nausea and prickle tongue; amoxicillin and erythromycin can cause diarrhea, nausea, glossitis, allergic urticaria, rash, and drug fever.

Then, the main problem that has troubled clinicians in recent years is the increasing drug resistance of Helicobacter pylori. Data released at the recent 6th Helicobacter pylori Clinical Diagnosis and Treatment Forum showed that due to the increase in drug resistance, the eradication rate of Helicobacter pylori with traditional triple therapy is declining year by year. Currently, the eradication rate of triple therapy in some areas has dropped to around 65%.

Helicobacter pylori quadruple therapy

As the eradication rate of Helicobacter pylori with triple and quadruple therapy decreases year by year, Helicobacter pylori probiotic therapy has received widespread attention and recognition at the Sixth National Clinical Forum on Helicobacter pylori Infection and Digestive Diseases and the Roundtable Conference on New Pathways for Helicobacter pylori Treatment.

Experts such as Du Yiqi and Hu Fulian gave a detailed introduction to the probiotic therapy for Helicobacter pylori:

Introduction to Probiotic Therapy:

Probiotic therapy refers to the method of adding probiotic preparations to the traditional triple or quadruple therapy, or directly using Wei Yue Ke probiotic preparations to eradicate Helicobacter pylori.

Advantages of probiotic therapy:

Current clinical studies at home and abroad have shown that probiotic therapy can increase the eradication rate of triple and quadruple vaccines by 10-20%, and reduce the adverse reactions of triple and quadruple vaccines by more than 20%.

Problems with probiotic therapy:

The main question at present is whether probiotics are more effective when used in combination with triple or quadruple therapy or alone, which remains to be verified.

Helicobacter pylori post-healing care

1. To change the way of eating, it is advisable to choose the separate dining system or use serving chopsticks.

2. Drink boiled water instead of raw water, eat cooked food instead of raw food, and sterilize milk before drinking.

3. Experiments have shown that patients with ulcers are also at risk of spreading the disease when kissing others, so they should be vigilant.

4. Develop good hygiene habits and wash your hands before meals and after going to the toilet. Tableware that is used frequently must also be strictly disinfected.

5. Do not place cleaning supplies such as toothbrushes in the bathroom. Make sure to place them in a ventilated place. Hygiene also requires regular ventilation and sunlight exposure. If the bathroom is on the shady side, ultraviolet light can be used for 5-10 minutes.

6. Go to the hospital regularly for Helicobacter pylori examination.

7. Use probiotic preparations regularly to improve gastrointestinal microecology and enhance gastrointestinal immunity.