When a part of the body is diseased, changes will generally occur in a certain place on the surface of the body. This is what Chinese medicine calls the holistic concept. The human body is an organic whole. Changes in one element within the body will affect changes in another element. We should observe our bodies more in our daily lives to see if any parts have changed, so that we can detect and treat them early. For example, we find that a lot of black moles suddenly appear on our face. Moles can be divided into broad and narrow meanings. The broad meaning includes various congenital and acquired melanocytic nevi, sebaceous nevi, etc. The term "mole" in medicine is used in a narrow sense, also known as nevus cell nevus, pigmented nevus, melanocytic nevus or common acquired melanocytic nevus, and does not include congenital melanocytic nevus. Mole is the most common benign skin tumor in humans. It is a skin manifestation caused by an increase in melanocytes in the epidermis and dermis. Depending on the location of nevus cells in the skin, they can be divided into junctional nevus, mixed nevus and intradermal nevus. Flat lesions suggest junctional nevi, slightly elevated lesions are mostly compound nevi, while papillomatous lesions and almost all hemispherical and pedunculated lesions are intradermal nevi. Causes It can be caused by many reasons and there is no definitive answer yet. It is generally believed that the occurrence of moles is related to genetic factors and environmental factors, mainly ultraviolet rays. Clinical manifestations It usually starts to appear after the age of two. It can occur on the skin and mucous membranes of any part of the body. The lesions are flat or slightly raised macules or maculopapules, which may also be hemispherical, papilloma-like or pedunculated, with a smooth surface, with or without hair, and may be single, a few to dozens in number. Due to the different types and contents of pigments in nevus cells, skin lesions may appear brown, bluish black or black, while non-pigmented lesions are mostly skin-colored. Depending on the location of nevus cells in the skin, they can be divided into junctional nevus, mixed nevus and intradermal nevus. Flat lesions suggest junctional nevi, slightly elevated lesions are mostly compound nevi, while papillomatous lesions and almost all hemispherical and pedunculated lesions are intradermal nevi. The disease progresses slowly and is often asymptomatic. Moles with atypical appearance may become malignant, such as very dark moles, uneven pigmentation, uneven or irregular edges, unclear boundaries, left-right asymmetry, and statistically larger than 5 mm in diameter. Moles located in the nail grooves and nails, extremities, oral mucosa, conjunctiva, vagina, and foreskin are more likely to become malignant melanomas than moles located in other places. examine Histopathological examination revealed nested nevus cells without dendrites in the skin. diagnosis Generally, the diagnosis can be made clinically, and pathological examination is performed for those suspected of malignancy. Differential Diagnosis Differentiate from diseases with pigmented skin lesions, such as senile melasma: it occurs on exposed parts of the body of middle-aged and elderly people, such as cheeks, neck, back of hands and forearms, and is mostly scattered brown in color, with small round, oval or irregular shapes, smooth or slightly raised patches of varying sizes. Histological examination showed an increase in normal melanocytes without malignant transformation. complication May be complicated by infection. Most grow slowly or remain unchanged for many years, but spontaneous degeneration rarely occurs. Some types of moles may turn into malignant ones, thus endangering life. treat No treatment is usually required. Junctional nevi and compound nevi occurring on the palms, soles, waist, armpits, groin and other areas prone to friction should be considered for surgical removal when the following conditions occur: ① sudden increase in size; ② blackening or mottled color; ③ erosion, ulceration, bleeding or swelling on the surface; ④ conscious pain or itching; ⑤ satellite lesions appear in the surrounding areas. Laser treatment is also possible. |
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