What to do if you are allergic to serum

I believe everyone has experienced allergies before. If those with severe allergies are not desensitized in time, they may face life-threatening danger, so it needs everyone's attention. Serum allergy is similar to other allergic reactions, often manifested as nausea, diarrhea, and in severe cases, difficulty breathing. So what if you are allergic to serum? At this time, it is necessary to ask a doctor for relevant treatment and desensitization in time.

Skin allergy test-serum allergy test

1. Methods and Contents

The following methods can be used for allergy tests for various antimycins (serum).

1. After local disinfection with 75% ethanol, first inject normal saline intradermally on the flexor side of the forearm as a control, take 0.1ml of serum and dilute it to 1ml with normal saline, and use 0.1ml of this dilution to inject intradermally about 10cm above the forearm control.

2. Check 20 minutes after injection. If only the skin papule at the serum injection site rapidly increases to more than 1 cm and has pseudopodia or irregular stripes, while the control has no reaction or a slight reaction, it is positive. If both the serum injection site and the control have no reaction or a slight reaction, it is negative.

Allergy treatment

3. Inject diluted serum once every 20 minutes and observe whether there is any reaction after each injection; if there is no reaction, give the original dose next time. If there is no reaction after intramuscular injection of 0.5 ml of undiluted serum, the remaining amount can be injected once. When implementing this method, 1 ml of 0.1% epinephrine should be prepared to prevent accidents.

4. Tetanus antimycin desensitization also uses the following method. When used for preventive medication, a total of 4 intramuscular injections are given, with an interval of 20 minutes between each injection. The serum is diluted 1:10 and injected 3 times with 1.0ml, 2.0ml, and 3.0ml each. If there is no reaction, the remaining amount is injected intramuscularly once without dilution.

5. Small-dose desensitization method: Considering that the desensitization process may occasionally cause severe reactions, if there is sufficient time, this method can be used to avoid severe reactions. 6. Give a total of 12 subcutaneous injections, with 20 minutes between each injection. Observation and treatment are the same as above. First, inject serum 1:100 dilution 4 times, 0.2, 0.4, 0.7, 1.0 ml respectively; finally, inject undiluted antitoxin 4 times, 0.1, 0.2, 0.3, 0.4 ml respectively; 7. If there is no reaction after the last injection, inject the remaining amount intramuscularly once.

2. Clinical manifestations

It is characterized by sudden onset and fierce force. 50% of children develop symptoms within 5 minutes after receiving the antigen.

Symptoms of anaphylactic shock may involve multiple systems, with the circulatory system being the most obvious.

1. Circulatory system manifestations: Due to vasodilation and plasma exudation, symptoms include pale complexion, cold sweat, cold limbs, palpitations, weak pulse, decreased blood pressure, and shock. In severe cases, the heart may stop beating.

2. Respiratory system manifestations: Due to edema and spasm of the laryngeal, trachea, and bronchial tubes or pulmonary edema, respiratory secretions increase, resulting in shortness of breath, chest tightness, holding breath, wheezing, cyanosis, and even death due to suffocation.