Serum magnesium is high

In order to let everyone know more about their own physical condition, the contents of serum magnesium and other related indicators are introduced to everyone in detail. High serum magnesium often indicates hypomagnesemia, renal magnesium loss, malnutrition-induced emaciation in children and other diseases. Low serum magnesium is clinically caused by hyperthyroidism, advanced liver cirrhosis, and ethanol poisoning. See the following for details.

Clinical significance

(1) Increased serum magnesium:

① Kidney disease: Any disease that affects the glomerular filtration rate can cause serum magnesium to be retained and increased. Such as oliguria in chronic nephritis, uremia, acute or chronic renal failure, etc.

② Endocrine diseases: such as hypothyroidism (myxedema), hypoparathyroidism, Addison's disease, untreated diabetic coma (rapid decline after treatment).

③ Improper treatment measures: Anyone who is poisoned by improper treatment with magnesium preparations.

④ Other diseases: multiple myeloma, severe dehydration, arthritis, acute viral hepatitis, amoebic liver abscess, oxalic acid poisoning, etc.

(2) Decreased serum magnesium:

① Digestive tract loss: long-term fasting, malabsorption or long-term loss of gastrointestinal fluid. Such as chronic diarrhea, malabsorption syndrome, intestinal fistula or biliary fistula after surgery, severe vomiting after long-term suction of gastric juice, ethanol poisoning, etc.

② Endocrine diseases: Hyperthyroidism, hyperparathyroidism, correction of diabetic acidosis, primary aldosteronism and long-term use of corticosteroids all increase urinary magnesium excretion.

③ Improper treatment measures: Patients treated with diuretics such as thalidomide or chlorothiazide did not supplement magnesium in time. Long-term intravenous infusion without magnesium rehydration.

④ Other diseases: Acute pancreatitis can form magnesium soaps around the pancreas; advanced liver cirrhosis can cause secondary aldosteronism; in addition, ascites and diuresis; hypoalbuminemia can reduce the amount of magnesium binding; acute myocardial infarction, acute ethanol poisoning, neonatal hepatitis, infant intestinal resection, etc.

(3) Increased urinary magnesium excretion: seen in polyuria due to various reasons, including long-term use of diuretics, renal tubular acidosis, primary aldosteronism, hypercortisolism, late stage of diabetes treatment, hyperparathyroidism, corticosteroid treatment and tumor bone metastasis.

(4) Decreased urinary magnesium excretion: This occurs in patients with long-term fasting, anorexia, and malabsorption. It may also be reduced in patients with hypoparathyroidism and adrenal cortex insufficiency.

Note:

(1) The amounts of reagents and samples can be varied proportionally according to the requirements of different instruments.

(2) If the test result is outside the test range, the sample should be diluted and tested again, and the factor adjusted or the result multiplied by the dilution factor.

(3) Accuracy of results: instrument calibration and control of measurement temperature and time.

(4) The doctor makes a clinical diagnosis based on clinical symptoms and other test results.