Reasons for high hypersensitive C-reactive protein

In life, the human body is prone to inflammation. If you do not pay attention to hygiene, you are susceptible to bacterial infection. These phenomena will not only affect your health, but also easily lead to high levels of hypersensitive C-reactive protein_high-sensitivity C-reactive protein. Therefore, everyone must develop a good habit of living to avoid these situations. So what are the reasons for high levels of hypersensitive C-reactive protein_high-sensitivity C-reactive protein?

First, hypersensitive C-reactive protein_the reason for high hypersensitive C-reactive protein. High levels of hypersensitive C-reactive protein are not specific and will increase in cases of inflammation, tissue damage, etc. High-sensitivity C-reactive protein, the normal human serum level is less than 10ug/ml. In cases of myocardial infarction, rheumatic activity, tissue damage, malignant tumors, surgical trauma and various acute or chronic infections, CRP may increase rapidly after 4 to 6 hours; as the condition improves, it will quickly drop to normal.

Second, C-reactive protein (CRP) is one of the acute phase response proteins. In 1930, Tillett and Fransic of the AVERY Laboratory of the Rockefeller Institute in the United States discovered that the serum of patients with acute infection could react with the C polysaccharide on the cell wall of Pneumococcus to precipitate. Later, it was confirmed that the protein involved in the reaction was a protein, so it was called C-reactive protein. The CRP gene is located on chromosome 1 q23 and its sequence is highly conserved. CRP is a member of the penetratin family with a relative molecular mass of 115×10^3. It is composed of 5 identical subunits bound by non-covalent bonds to form a symmetrical annular pentaspheric structure with a hole-shaped structure in the middle. The concave surface contains a ligand binding site. Each subunit has 206 amino acid residues and a relative molecular mass of 23×10^3.

Hypersensitive C-reactive protein_Reasons for high hypersensitive C-reactive protein. Protein C is the body's response to bacterial infection. It means that the erythrocyte sedimentation rate in the body becomes high. The reasons for the high erythrocyte sedimentation rate include acute bacterial inflammation, severe chronic bacteria, and infectious diseases caused by these bacteria such as tuberculosis. In addition, when inflammations such as myocarditis and meningitis occur, high-sensitivity C-reactive protein levels may also be caused.