What are the side effects of Anlufan?

Anlufan is a drug for treating schizophrenia. Generally, it can be taken orally once a day, but the dosage can be adjusted appropriately according to the patient's age and condition. Generally speaking, this drug will not cause side effects to patients, but some patients will experience systemic adverse reactions, the most common of which are fever, migraine, bloating, tightness in the throat, etc.

1. Indications

Used to treat schizophrenia. The efficacy of aripiprazole in the treatment of schizophrenia was established in short-term (4 and 6 weeks) controlled trials in patients with schizophrenia. Physicians who select aripiprazole for long-term treatment should periodically reassess the long-term effectiveness of the drug for their individual patients.

2. Usage and Dosage

Adults: Orally, once daily. The recommended starting dose and therapeutic dose of aripiprazole is 10 or 15 mg/day, which is not affected by food intake. Systematic evaluation showed that the clinically effective dose range of aripiprazole is 10 to 30 mg/day. The efficacy of high doses was no better than that of low doses of 10 mg or 15 mg/day. The dosage should not be increased within 2 weeks of medication (the time required for the drug to reach steady state). After 2 weeks, it can be adjusted appropriately based on individual efficacy and tolerance, but the dosage increase rate should not be too fast. The dosage for special populations generally does not need to be adjusted based on age, gender, race, or renal or hepatic impairment.

3. Side Effects

1. Body: Common - influenza syndrome, fever, chest pain, stiffness (including neck and limbs), neck pain, pelvic pain; Uncommon - facial edema, suicidal tendency, malaise, migraine, chills, photosensitivity, tightness (including abdomen, back, limbs, head, jaw, neck and tongue), jaw pain, bloating, abdominal distension, chest tightness, sore throat; Rare - candidiasis, heaviness of the head, tightness of the throat, Mendelsohn's syndrome, heat stroke.

2. Cardiovascular system: Common - tachycardia (including ventricular and supraventricular), hypotension, bradycardia; Uncommon - palpitations, hemorrhage, heart failure, myocardial infarction, cardiac arrest, atrial fibrillation, atrioventricular block, QT interval prolongation, extrasystoles, myocardial ischemia, deep vein thrombosis, angina pectoris, pallor, cardiopulmonary dysfunction, phlebitis; Rare - bundle branch block, atrial flutter, vasovagal reaction, cardiomegaly, thrombophlebitis, cardiopulmonary failure.

3. Digestive System: Common - nausea and vomiting; Uncommon - increased appetite, dysphagia, gastroenteritis, flatulence, dental caries, gastritis, gingivitis, gastrointestinal bleeding, hemorrhoids, gastroesophageal reflux, periodontal abscess, fecal incontinence, rectal bleeding, gastritis, colitis, tongue edema, cholecystitis, oral ulcer, oral candidiasis, belching, fecal impaction, cholelithiasis; Rare - esophagitis, hematemesis, intestinal obstruction, gingival bleeding, hepatitis, peptic ulcer, glossitis, melena, duodenal ulcer, cheilitis, hepatomegaly, pancreatitis.