What is the normal blood oxygen level_normal blood oxygen concentration

Humans rely on oxygen to survive, and oxygen can maintain our normal breathing function. When the oxygen in the air is particularly thin, it will cause people to have difficulty breathing. Therefore, people with poor heart or lung function should not go to plateau areas. In addition, the blood pressure in the body is very normal. Understand the normal blood oxygen range and normal blood oxygen concentration.

Medical principles

Humans rely on oxygen to survive. After oxygen is inhaled from the lungs, it enters the blood through the capillaries and is transported by the blood to various organs or cells in the body for use. The higher the oxygen content in the blood, the better the person's metabolism.

Of course, high blood oxygen content is not a good thing. The blood oxygen in the human body has a certain saturation. Too low will cause insufficient oxygen supply to the body, and too high will cause aging of cells in the body.

Both O2 and CO2 exist in the blood in two forms: physically dissolved and chemically bound. Gas and hemoglobin exist in the form of complexes. If the oxygen concentration is high, hemoglobin will complex with oxygen. If the carbon dioxide concentration is high, hemoglobin will complex with carbon dioxide. In the body's arterial blood, the oxygen concentration is high, and in the body's venous blood, the carbon dioxide concentration is high.

Medical terminology

Oxygen partial pressure (PO2) refers to the tension generated by oxygen molecules physically dissolved in plasma (so it is also called oxygen tension). In 100 ml of blood at 37°C, oxygen dissolved in a physical state can produce an oxygen partial pressure of 0.133 kPa (1 mmHg) for every 0.003 ml. When a normal person is at rest and breathes sea level air, the oxygen physically dissolved in the arterial blood is about 0.3 ml%, the partial pressure of oxygen in the arterial blood (PaO2) is about 13.3 kPa (100 mmHg); the normal partial pressure of oxygen in the venous blood (PvO2) is about 5.32 kPa (40 mmHg).

PaO2 mainly depends on the level of alveolar oxygen partial pressure (PAO2), the amount of oxygen diffused into the blood through the alveolar membrane, and the ratio of alveolar ventilation to pulmonary blood flow. If the oxygen partial pressure of the outside air is low or alveolar ventilation is reduced, the alveolar oxygen partial pressure will decrease; or if diffusion disorder or ventilation/blood flow imbalance causes an increase in the functional or anatomical shunt of pulmonary arteriovenous blood, PaO2 may decrease.

Oxygen content refers to the number of milliliters of oxygen contained in 100 milliliters of blood, including the oxygen actually bound to hemoglobin and the oxygen dissolved in plasma. Normal arterial blood oxygen content is about 19.3 ml%, and mixed venous blood oxygen content is about 12 ml%. The oxygen content in the blood mainly depends on PaO2 and the quality and quantity of hemoglobin. A significant decrease in PaO2 or a decrease in the ability of hemoglobin to bind oxygen, which reduces hemoglobin saturation, or a decrease in the amount of hemoglobin per unit volume of blood, can all reduce the oxygen content.

The oxygen content depends on the amount of hemoglobin in a unit volume of blood and its ability to bind oxygen. If the hemoglobin content decreases (anemia) or the ability of hemoglobin to bind oxygen decreases (such as methemoglobin, carboxyhemoglobin), the oxygen capacity decreases and the oxygen content also decreases. If the amount and properties of hemoglobin per unit volume of blood are normal, the oxygen saturation of hemoglobin will decrease only due to the decrease in oxygen partial pressure. At this time, the oxygen content is reduced, but the oxygen capacity is normal.