How to use omeprazole to treat gastritis

Modern medicine has a wealth of experience in the treatment of gastritis, and many drugs that can treat gastritis have emerged, which reduce the burden on people's bodies and ensure that gastritis does not cause greater harm to the body. For example, there are many examples of using omeprazole to treat gastrointestinal diseases in modern medicine. Let’s take a look at how to use omeprazole to treat gastritis. I hope everyone can understand.

usage :

1. (1) Gastric and duodenal ulcers: 20 mg each time, once in the morning. The treatment course for duodenal ulcer is usually 2 to 4 weeks, and the treatment course for gastric ulcer is 4 to 8 weeks. For patients with refractory ulcers, 20 mg can be used twice a day or 40 mg can be used once a day. (2) Reflux esophagitis: 20-60 mg per day, once a day. (3) Zollinger-Ellison syndrome: The initial dose is 60 mg once a day, which can be adjusted to 20-120 mg per day to control symptoms. If the dose is greater than 80 mg per day, it should be administered in 2 divided doses.

2. Intravenous injection: When used to treat peptic ulcer bleeding, it can be given by intravenous injection, 40 mg each time, once every 12 hours, for 3 consecutive days. The first dose may be doubled.

3. Intravenous drip: Patients with heavy bleeding can also use an initial dose of 80 mg intravenous drip, followed by 8 mg per hour to maintain bleeding until the bleeding stops.

4. Dosage for hepatic impairment: Use with caution in patients with severe hepatic impairment and halve the dose if necessary.

Adverse Reactions

1. There may be dry mouth, mild nausea, vomiting, abdominal distension, constipation, diarrhea, abdominal pain, etc.; elevated alanine aminotransferase (ALT), aspartate aminotransferase (AST) and bilirubin may also occur, which are generally mild and short-lived and do not affect treatment in most cases. Other foreign data reported that manifestations of atrophic gastritis can be observed in gastric biopsy specimens of patients treated with omeprazole for a long time.

2. Neuropsychiatric system: may cause paresthesia, dizziness, headache, drowsiness, insomnia, peripheral neuritis, etc.

3. Metabolic/endocrine system: Long-term use of omeprazole may lead to vitamin B12 deficiency.

4. Carcinogenicity: Animal experiments have shown that omeprazole can cause hyperplasia of enterochromaffin cells, the main endocrine cells in the fundus and body of the stomach. Long-term use of the drug may also cause gastric carcinoid.

5. Others: may include rash, male breast development, hemolytic anemia, etc.