You may not be too familiar with the name "vitiligo", but I believe everyone must have heard of vitiligo, and vitiligo is vitiligo. Vitiligo will cause some white spots on the surface of human skin. These white spots are systemic and can appear all over the body. The face and arms are particularly prone to white spots, which have a great impact on appearance and, in more serious cases, can cause great psychological stress. The following is an introduction to its removal treatment methods. 1. Medication (1) Oral administration of psoralen and its derivatives such as methoxsalen followed by exposure to ultraviolet light. (2) Long-term use of large doses of vitamins such as B vitamins, vitamin C, and vitamin P. (3) Treatments include drugs containing copper, such as 0.5% copper sulfate solution taken orally. (4) Immunomodulators: oral levamisole, freeze-dried Bacillus Calmette-Guérin (BCG) intramuscular injection, oral bovine placenta, etc. (5) Topical application of skin irritants causes inflammation of the skin and promotes pigmentation. Commonly used agents include 30% psoralea corylifolia tincture, nitrogen mustard alcohol, phenol (pure carbolic acid), 25% to 50% trichloroacetic acid, and blister beetle tincture. This method is only suitable for small skin lesions, and blisters may appear on the lesions after application. (6) Corticosteroids: Various corticosteroids such as beclomethasone dipropionate ointment, halometasone cream, triamcinolone urea ointment, etc. are used for local packing treatment. 2. Surgery Patients with stable skin lesions and no progression can undergo autologous epidermal transplantation. 3. Depigmentation therapy It is suitable for those with large skin lesions that exceed more than half of the body surface area. 3% to 20% hydroquinone monobenzyl ether cream can be applied externally. 4. Physical therapy Treatment is with narrow-wave ultraviolet light, long-wave ultraviolet light or 308nm excimer laser. prevention 1. Reduce the intake of contaminated food, correct picky eating, and develop a scientific diet recipe. 2. Reduce the inhalation of harmful gases and choose a place with fresh air when doing morning exercises or sports. 3. Pay attention to labor protection. 4. Pay attention to the pollution caused by house decoration. 5. Keep a happy mood. Causes 1. Genetic theory Vitiligo can occur in twins and families, indicating that heredity plays an important role in the onset of vitiligo. Studies have shown that vitiligo has incomplete penetrance and there are multiple pathogenic sites on the gene. 2. Autoimmunity theory Vitiligo can be combined with autoimmune diseases such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma, etc. 3. Psychological and neurochemical theory Mental factors are closely related to the onset of vitiligo. Most patients suffer from mental trauma, excessive tension, depression or frustration during the onset or development of skin lesions. The degeneration of nerve endings in the white spots also supports the neurochemical theory. 4. Melanocyte self-destruction theory Vitiligo patients can produce antibodies and T lymphocytes in their bodies, indicating that the immune response may lead to the destruction of melanocytes. 5. Trace element deficiency theory The levels of copper or ceruloplasmin in the blood and skin of vitiligo patients are reduced, resulting in reduced tyrosinase activity, thus affecting the metabolism of melanin. 6. Other factors Trauma, sun exposure and some photosensitive drugs can also induce vitiligo. |
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