Advantages and disadvantages of triple therapy for the treatment of Helicobacter pylori

Due to various reasons and some bad living habits, many people suffer from gastrointestinal diseases. There are many types of diseases. Many people must have heard of Helicobacter pylori, but not many know its specific meaning. However, no matter what, we still need to learn more about some methods of treating this disease. So, is triple therapy effective in treating Helicobacter pylori?

1. Main Functions

1. Prevent recurrence of the disease.

Triple therapy is to add several immunity-enhancing drugs to traditional therapy, so that Helicobacter pylori is less likely to recur after treatment.

2. Treat both the symptoms and the root causes.

Traditional treatments only treat the symptoms and not the root cause, and cannot cure Helicobacter pylori. The "triple therapy" uses RNA interference technology to analyze the key genes that cause the disease. It can quickly and effectively target the lesions, reach the affected area, eliminate the cause fundamentally, activate the activity of the body's own immune cells, and completely cure Helicobacter pylori.

3. Quick cure.

It has extremely strong permeability and can freely pass through the cell membrane, thus minimizing the time it takes for the drug to reach the lesion. It can be released continuously at the lesion for 24 hours, further shortening the healing time.

2. Advantages

Compared with single antibiotic therapy and dual therapy, triple therapy has the advantage of high eradication rate. In previous years, when H. pylori resistance was not as common as it is today, the eradication rate of triple therapy could reach 85%-95%.

Disadvantages

The first is the issue of side effects. Almost all commonly used antibiotics have certain side effects. For example, metronidazole, the two most commonly used antibiotics in the triple therapy, can cause nausea and prickle tongue; amoxicillin and erythromycin can cause diarrhea, nausea, glossitis, allergic urticaria, rash, and drug fever. Secondly, the main problem that has troubled clinicians in recent years is the increasing drug resistance of Helicobacter pylori. Data released at the recent 6th Helicobacter pylori Clinical Diagnosis and Treatment Forum showed that due to the increase in drug resistance, the eradication rate of Helicobacter pylori with traditional triple therapy is declining year by year. Currently, the eradication rate of triple therapy in some areas has dropped to around 65%. The most commonly used triple combination prescription is: 110 mg of potassium citrate bismuth, 4 times a day, orally 30 minutes before meals and before bedtime; 500 mg of amoxicillin, 0.2 g of metronidazole, three times a day. Omeprazole 10 mg, once a day, four weeks as a course of treatment.