What should I do if my bone marrow hematopoietic function is weak?

Hematopoietic dysfunction is a common disease in clinical practice. There are many causes for it. For example, with the increasing incidence of cancer, some tumor patients will use a large amount of chemotherapy or radiation to treat them, which will later lead to symptoms such as severe bone marrow suppression, insufficient hematopoietic function, and decreased immunity. Leukemia patients may also suffer severe bone marrow damage during the bone marrow transplant process. The side effects of certain drugs or chemical poisons can cause great damage to the hematopoietic function of the bone marrow. Autoimmune diseases can also cause damage to bone marrow hematopoietic cells, leading to anemia in patients, which can be life-threatening in severe cases. So what should we do if our bone marrow hematopoietic function is weak?

1. Hematopoietic dysfunction

Hematopoietic dysfunction can be caused by a variety of reasons and is relatively common in clinical practice. For example, with the increase in the incidence of tumors, some cancer patients will experience severe bone marrow suppression, insufficient hematopoietic function, and further decreased immunity after using high-dose radiotherapy and chemotherapy, thus forming a vicious circle. Severe bone marrow damage caused during the bone marrow transplantation process in leukemia patients, the toxic side effects of certain drugs and the destruction of bone marrow hematopoietic function by chemical poisons, and various autoimmune diseases (such as aplastic anemia, idiopathic thrombocytopenic purpura and other blood diseases; serious immune diseases such as lupus erythematosus, multiple sclerosis, and immune system disorders) can also cause destruction of bone marrow hematopoietic cells, leading to anemia, bleeding, and susceptibility to infection in patients, which can be life-threatening in severe cases. The medical community at home and abroad has limited treatment options for the above-mentioned diseases, and the results are not ideal. Those with severe illness require bone marrow transplantation, but bone marrow donors are difficult to find, treatment costs are high, and the risk is great. Re-establishing normal hematopoietic and immune systems is the key to treating these diseases and is also a major challenge currently facing the medical community.

Leukemia is a type of clonal malignant disease caused by abnormal hematopoietic stem cells. The leukemia cells in its clones lose the ability to further differentiate and mature and stagnate at different stages of cell development. Leukemia cells proliferate and accumulate in the bone marrow and other hematopoietic tissues and infiltrate other organs and tissues, while suppressing normal hematopoiesis. The clinical manifestations are anemia, bleeding, infection and symptoms of infiltration of various organs.

2. Causes of Leukemia

The exact cause of human leukemia remains unknown. Many factors are thought to be involved in the development of leukemia. The virus may be a major factor. In addition, there are other factors such as genetic factors, radiation, chemical poisons or drugs. Certain chromosomal abnormalities are directly related to the occurrence of leukemia. Chromosome breakage and translocation can cause the position of oncogenes to move and become activated. Changes in the gene structure within chromosomes can directly cause cell mutations. Reduced immune function is conducive to the onset of leukemia.

1. Viruses

It has long been confirmed that type C RNA tumor viruses, or retroviruses, are the cause of spontaneous leukemia in mammals such as mice, cats, cattle, sheep, and primates. This virus can synthesize a DNA copy, namely a provirus, according to the RNA sequence through endogenous reverse transcriptase, which can induce malignant transformation when inserted into the host's chromosomal DNA.

2. Genetic factors

Genetic factors are associated with the development of some leukemias. 8.1% of leukemia patients had a family history of leukemia, while only 0.5% of the control group had a family history of leukemia. The incidence of acute lymphoblastic leukemia in people who marry close relatives is 30 times higher than the expected value. Certain genetic diseases with chromosomal abnormalities and breaks are often accompanied by a higher incidence of leukemia, such as Down syndrome, congenital vascular dilatation erythema (Bloom syndrome) and Fanconi anemia.

Prevention of Leukemia

1. Avoid exposure to excessive X-rays and other harmful radiation. People engaged in radiation work must take personal protection measures. Pregnant women and infants should especially avoid exposure to radiation.

2. Prevent and treat various infections, especially viral infections. Such as type C RNA virus.

3. Use certain medicines with caution. For example, long-term use or abuse of chloramphenicol, phenylbutazone, certain antiviral drugs, certain anti-tumor drugs and immunosuppressants should be avoided.

4. Avoid contact with certain carcinogens and do a good job in occupational protection and monitoring. For example, in the production process of phenol, chlorobenzene, nitrobenzene, spices, medicines, pesticides, synthetic fibers, synthetic rubber, plastics, dyes, etc., be careful to avoid contact with harmful and toxic substances.

5. Regular surveys should be conducted on people at high risk of leukemia, with special attention paid to the warning signs and early symptoms of leukemia. Those who have the conditions can take Tianxian Vitality Source for preventive treatment.