What are the causes and hazards of splenomegaly

Splenomegaly generally refers to an enlarged spleen, which is also a common problem in clinical practice. Strictly speaking, splenomegaly is a pathological phenomenon that will have a certain impact on human health. Therefore, the problem of splenomegaly should also be taken seriously. If the symptoms of splenomegaly persist for a long time, it may induce many diseases. The spleen is a very important organ in the body and plays a very important role in the functioning of various body functions. Therefore, the health of the spleen is also a concern for most people. An enlarged spleen must be taken seriously, and its cause must be identified when treating it to prevent it from causing greater harm to the human body.

1. Reasons

(1) Infectious splenomegaly. Various acute and chronic infectious diseases, such as acute viral hepatitis, typhoid sepsis, systemic miliary tuberculosis, subacute bacterial endocarditis and schistosomiasis.

(2) Congestive splenomegaly. Such as cirrhosis, portal vein or splenic vein thrombosis.

(3) Hyperplastic splenomegaly. Anemia of various causes, certain hemoglobinopathies, myelofibrosis and true polycythemia, etc.

(4) Dipping splenomegaly. Such as cerebroside-containing reticuloendothelial disease, phospholipid-containing reticuloendothelial disease, amyloidosis and hemochromatosis.

(5)Tumors and cysts. Such as leukemia, lymphoma, benign tumors, malignant tumors, true cysts and pseudocysts, etc.

2. Hazards

If the harm of an enlarged spleen is serious, it may lead to rupture and bleeding, and may even be life-threatening. It is recommended that you do not drink alcohol. The spleen is the largest blood storage organ in the body. Obstruction of blood return to the spleen caused by various reasons can cause congestive enlargement of the spleen, such as portal hypertension due to cirrhosis, portal vein and inferior vena cava thrombosis, tumor emboli, congenital or acquired vascular malformations; right heart failure caused by various reasons, constrictive pericarditis or large pericardial effusion can all cause congestion and enlargement of the spleen.

3. Note

The results vary depending on the cause of splenomegaly. For example, congestive splenomegaly caused by portal hypertension often leads to hypersplenism in the late stage. Hypersplenism causes excessive destruction of blood cells as the blood passes through the spleen, resulting in a decrease in the counts of red blood cells, white blood cells, and platelets, accompanied by a series of symptoms. In short, a decrease in granulocytes can easily lead to infection, a decrease in red blood cells, that is, anemia, can cause symptoms such as pale complexion, weakness, and a decrease in platelets can easily lead to bleeding and the body cannot stop bleeding on its own.