How is rotavirus enteritis treated with medication?

Rotavirus enteritis is a common acute gastrointestinal disease in infants and young children. It is also highly contagious and is mainly transmitted to children through the digestive tract. After patients get this enteritis, they often develop acute high fever reactions, diarrhea and vomiting. Generally, the illness is relatively short and can achieve good results through certain treatments. Generally, there are no sequelae. It should be understood that rotavirus enteritis often occurs in autumn, so it is also called autumn diarrhea. Rotavirus enteritis must be treated with medication in a timely manner. There are many drug treatment methods. The more common drugs include loperamide, diphenoxylate, etc.

1. Loperamide (loperamide, phenbutamol, Imodium)

This product has a direct effect on the intestinal wall, inhibiting intestinal peristalsis and contraction. The oral dosage for adults is 2-4 mg/time, 1-3 times a day; for children under 5 years old, 1 drop/kg?time (drops), 2-3 times a day. After application, constipation, dizziness, nausea, dry mouth and rash may occasionally occur. It should be used with caution in patients with abnormal liver function and is contraindicated in pregnant women and children under 2 years old.

2. Diphenoxylate (diphenoxylate, phenethylamine, antidiarrheal)

This product can increase intestinal tension and inhibit intestinal peristalsis. It is a non-specific and effective drug for controlling acute and chronic diarrhea. It has a rapid antidiarrheal effect and is limited to symptomatic treatment for some stubborn diarrhea. It is suitable for acute and chronic diarrhea and diarrhea caused by intestinal dysfunction. Oral administration: 2.5-5 mg/time, 3-4 times/day for adults; 1.25-2.5 mg/time, 3-4 times/day for children over 2 years old.

The dosage should be reduced promptly after diarrhea is controlled. Adverse reactions such as rash, nausea, dizziness, insomnia, dry mouth, and abdominal discomfort are occasionally seen. It disappears after reducing the dosage or stopping the drug. Overdose can cause severe respiratory depression and coma. Long-term use can produce euphoria and cause addiction. It is contraindicated for children under 2 years old and those with abnormal liver function.

3. Smeta (dioctahedral montmorillonite)

It is an antidiarrheal agent that protects the mucous membrane of the entire digestive tract. This medicine is packaged in bags. The main ingredient of each bag is 3g of dioctahedral montmorillonite, which has a strong selective fixation and inhibition effect on viruses, bacteria and the toxins they produce in the digestive tract. It has a strong covering ability on the digestive tract mucosa, and by combining with mucus glycoproteins, it repairs the mucosa and improves the barrier effect of the mucosa against attacking factors. Oral administration: adults take 1 bag each time, 3 times a day, and use for 3 to 5 days depending on the situation. For children <1 year old, take 1 pack per day, divided into 3 times; for children 1-2 years old, take 2 packs per day, divided into 4 times; for children 3 years old and above, take 3 packs per day, divided into 3 times.

This disease is a self-limiting disease and most patients have a good prognosis. The condition of infected infants and young children is generally serious and the mortality rate is high. In recent years, the use of oral rehydration solutions (ORS) has significantly reduced deaths caused by diarrhea.