What are the contraindications of taking gout medicine

Gout is a type of joint disease, and its symptoms mainly include acute arthritis, chronic arthritis, uric acid urinary stones, etc. People with more severe gout may have symptoms such as imperfect kidney function and joint disability. Gout is often accompanied by symptoms such as hyperlipidemia, hypertension, and diabetes. This disease is extremely painful and has a great impact on life. Let us introduce the contraindications of taking gout medicines.

Gout is a crystal-related arthritis caused by the deposition of monosodium urate (MSU), which is directly related to hyperuricemia caused by purine metabolism disorders and/or decreased uric acid excretion. It specifically refers to acute characteristic arthritis and chronic tophi disease, mainly including acute onset arthritis, tophi formation, tophi-induced chronic arthritis, urate nephropathy and uric acid urinary stones. In severe cases, joint disability and renal insufficiency may occur. Gout is often accompanied by abdominal obesity, hyperlipidemia, hypertension, type 2 diabetes and cardiovascular disease.

1. Do not take any medicine on your own and seek medical attention immediately:

If gout attacks are treated with painkillers promptly, the symptoms can usually be relieved; even without medication, the pain symptoms can be relieved within two weeks. So some people just take the attitude of just bearing it when it hurts. However, causing joint pain is not the main harm of gout. Persistent high uric acid levels during the remission period are also constantly endangering health, aggravating joint damage while also endangering the kidneys. In addition, the duration of taking painkillers in the acute phase is generally about one week. If the pain does not improve significantly after taking the medicine for a week, you should seek medical attention immediately.

2. Medication must be standardized and regular:

Gout, like diabetes and hypertension, is a chronic disease and generally requires long-term medication. Once the medication is stopped, uric acid levels may rise and the disease may recur. The drug dosage can only be adjusted under the guidance of a specialist physician, and small doses of drugs should be used to control uric acid within the target range to reduce possible drug side effects and treatment costs. In addition, some drugs only have an auxiliary effect on the treatment of gout, such as sodium bicarbonate. In most uric acid-lowering treatments, sodium bicarbonate alone is often not enough.

3. Gout should be treated even when it is not in progress:

There is a type of patient who has very high uric acid levels but has never suffered from gout; there is another type of patient who has had gout attacks before, but the attacks were not very frequent and they just get by. It is important to make it clear to both types of patients that elevated uric acid levels require treatment even if they do not cause symptoms.

4. Do not stop taking medicine without authorization if it is ineffective:

Many people still experience gout attacks after starting to take uric acid-lowering drugs. This is not because the drugs are ineffective, but because the lowered blood uric acid concentration affects the urate in the tissue fluid, causing them to redistribute and deposit in the joints. It is not the case that "the more treatment, the worse the condition."

5. Pay attention to the impact between drugs:

Among hypoglycemic drugs, biguanides are widely used and suitable for obese diabetic patients. However, they can cause lactic acid accumulation in the body and reduce uric acid excretion. Therefore, gout patients need to be more cautious when using such drugs. Similarly, there are some antihypertensive drugs, such as furosemide, spironolactone, angiotensin-converting enzyme inhibitors (ACEI), etc. These drugs will reduce the excretion of uric acid and significantly increase the uric acid concentration in the body.