Knocking out cells is a common medical term. It is quite common in medicine, and is mainly seen in genital warts. Knocking out cells can cause problems such as hyperplasia, epidermal necrosis, and keratinization. Everyone should have a little understanding of medical knowledge, which can not only prevent the disease from getting worse, but also timely observe the current disease status on the test report. Koilocytes are "bottom cells" of squamous cells. After being damaged by HPV, (immature cells or reserve cells) accelerate the maturation of damaged cells to form surface squamous cells: the damage is mainly atypical hyperplasia, atypical keratinization and hollow cells, which is an important indicator for cytological diagnosis of low-grade lesions (CIN2 or mild atypical hyperplasia). Common in genital warts. Koilocytes are the "bottom cells" of squamous cells After being damaged by HPV, (immature cells or reserve cells) accelerate the maturation of damaged cells to form surface squamous cells: the damage is mainly atypical hyperplasia, atypical keratinization and hollow cells, which is an important indicator for cytological diagnosis of low-grade lesions (CIN2 or mild atypical hyperplasia). Common in genital warts. "Knockout cells"; explanation in academic literature Pathological examination showed papillary hyperplasia of squamous epithelium, enlarged cells in the upper stratum spinosum, large and darkly stained nuclei, binucleated or multinucleated, and perinuclear cavitation areas, which were called koilocytes. Immunohistochemical examination using avidin-biotin complex method detected HPV antigens in koilocytes as dark yellow or golden granules, with a positive rate of 50%. A few HPV virus particles were found, which were highly infectious. |
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