How can cirrhosis be cured?

Cirrhosis is a chronic disease. The causes of cirrhosis are generally worsening hepatitis leading to cirrhosis, or cirrhosis caused by drinking. Cirrhosis can cause symptoms such as weakness in the limbs, swelling of the abdomen and lower limbs, loss of appetite, dull complexion, vomiting, etc. When facing cirrhosis, treatment should be aggressive.

Treatment strategy

1. Drug treatment

1. Supportive treatment: Intravenous infusion of hypertonic glucose solution, pay attention to maintaining the balance of water, electrolytes, acid and alkali. Patients with more serious conditions can receive transfusions of albumin and fresh plasma.

2. Reduce portal vein pressure: propranolol or isoflavone.

3. Treatment of ascites: Potassium-sparing diuretics and albumin infusion can be used.

4. Antimicrobial drugs: Suitable for patients with complicated spontaneous peritonitis, mainly antimicrobial drugs targeting Gram-negative bacteria and Gram-positive cocci.

2. Surgical treatment

1. Surgical treatment of ascites: peritoneal-jugular drainage, transjugular intrahepatic portosystemic shunt. The latter can effectively reduce portal vein pressure, has little trauma and high safety, but is prone to induce hepatic encephalopathy. 2. Surgical treatment of portal hypertension: including portocaval shunt, porto-azygos shunt and splenectomy. 3. Liver transplantation: Suitable for end-stage liver disease that is resistant to conventional internal and external surgical treatments.

3. Prognosis

The prognosis is related to the cause, the degree of liver function compensation and complications. Cirrhosis caused by alcoholic cirrhosis, biliary cirrhosis, hepatic congestion, etc. is better than viral hepatitis cirrhosis and cryptogenic cirrhosis. Child-Pugh classification is closely related to prognosis, with grade A being the best and grade C being the worst. The cause of death is often complications such as hepatic encephalopathy, hepatorenal syndrome, and ruptured bleeding of esophageal-gastric varicose veins. The development of liver transplantation has significantly improved the prognosis of patients with cirrhosis.