What is the best treatment for oral leukoplakia

Oral leukoplakia is a relatively common oral disease, which is quite harmful to patients. If it is not treated in time, the disease is prone to recurrence. There are many treatments for oral leukoplakia. You should take vitamin A orally to increase your body's physical fitness. You can also apply cod liver oil to the areas of white spots, or use retinoic acid solution for local treatment. Both have good effects.

1. Apply cod liver oil to white spots

Patients with oral leukoplakia can use cod liver oil to rub the white spots for a long time, 2 to 3 times a day, and one to two months as a course of treatment, but do not use too much force. You can also take cod liver oil orally, or take 50,000 U of vitamin A. Close follow-up is required during conservative treatment.

2. Oral Vitamin A

Patients with oral leukoplakia can take vitamin A orally, 50,000 U per day, or retinoic acid 35-50 mg/d. Headache and dizziness may occur when taking the medicine for the first time, and the dosage can be reduced as appropriate. Usually, the patient can adapt to the disease after a few days. From the 2nd to 3rd week, gradually increase the dosage to 30-60 mg per day, divided into 3 doses. The course of treatment is about 1 to 2 months. Common side effects include dry lips and hair loss. It is contraindicated for patients with coronary heart disease, abnormal liver and kidney function and hyperlipidemia.

3. 0.2% retinoic acid solution is suitable for topical application

0.2% retinoic acid solution is suitable for topical application, but not for lesions accompanied by congestion and erosion. When applying, wipe off the saliva first, dip a small amount of solution with the finest brush and apply it along the white area. Be careful not to apply on the affected area of ​​patients with oral leukoplakia. Ointment preparations are not suitable because they cannot adhere to the lubricated mucosa inside the mouth. The new preparations of isotretinoin and arotinoid have basically the same effects as retinoic acid. Their main advantages are small dosage (0.5 mg per kilogram per day), low toxicity, and few side effects (dry lips and hair loss), but they are teratogenic.

4. Treatment with Chinese medicine Qingwei Xiehuo Decoction

The traditional Chinese medicine Qingwei Xiehuo Decoction has a good effect in treating oral leukoplakia. Generally, 5 to 7 doses of medicine can cure the disease. The following are some introductions, you may want to give it a try. You can use 15 grams of raw rehmannia, 10 grams of Akebia, 15 grams of bamboo leaves, 10 grams of Anemarrhena asphodeloides, 10 grams of Coptis chinensis, and 10 grams of licorice. Take it in decoction, 1 dose per day.

This is all we have to say about “What is the best method to treat oral leukoplakia”. I hope it can help the majority of patients and friends. For patients whose oral leukoplakia does not respond to long-term treatment and does not regress after treatment, if cracks, ulcers, or hardening of the base and significant surface thickening are found in the leukoplakia area, or if lesions have been proven to have precancerous changes, surgical resection should be performed as soon as possible.