The reason why lactate dehydrogenase is high is actually caused by them

Lactic acid bacteria are present in the cytoplasm of all body cells, and the normal range is between 100 and 300 U/L. If the blood sugar is found to be too high during the examination, it may be caused by reasons such as muscular dystrophy, liver disease, lung disease, heart disease, kidney disease, pulmonary infarction, pernicious anemia, shock, etc.

1. Causes of high lactate dehydrogenase

1. Muscular dystrophy: LDH4 and LDH5 in the blood of patients with muscular dystrophy are significantly elevated.

2. Liver disease: When the liver is diseased and liver cells are damaged, LDH4 and LDH5 in the blood will increase significantly. LDH5/LDH4<1 often indicates primary liver cancer. In acute hepatitis, LDH5 increases significantly, while LDH4 does not increase. Chronic hepatitis is manifested by a continuous increase in LDH5 or a decrease followed by an increase.

3. Lung disease: Serum LDH3 often increases in cases of lung disease. In patients with lung abscess, serum LDH3 and LDH4 are often elevated simultaneously with LDH5.

4. Heart disease: Serum LDH1 and LDH2 increase significantly in viral and rheumatic myocarditis, Keshan disease myocardial damage, and acute myocardial infarction.

5. Kidney disease: Serum LDH5 may increase in acute tubular necrosis, chronic glomerulonephritis and renal transplant rejection.

6. When the condition of a hepatitis B virus carrier worsens and becomes a hepatitis B patient, some liver cells are damaged and the levels of LDH4 and LDH5 in the serum will increase to varying degrees.

7. Improper treatment of hepatitis B, especially improper use of medication, and long-term use of the same medication can cause kidney toxicity. When nephrotoxicity occurs, the lactate dehydrogenase level in the serum will increase rapidly.

8. If hepatitis B is not treated appropriately and actively, it will develop to a certain extent and cause serious abnormalities in liver metabolism, leading to kidney failure, which will also cause an increase in lactate dehydrogenase levels.

9. Pulmonary infarction, pernicious anemia, shock and pleural effusion caused by tumor metastasis will cause elevated lactate dehydrogenase levels.

2. Causes of low lactate dehydrogenase

Lactate dehydrogenase is present in the cytoplasm of all tissue cells in the body, with the highest content in the kidneys. The normal range of serum lactate dehydrogenase is 100-300U/L. When lactate dehydrogenase is low, the common causes are as follows.

1. Errors occurred during the inspection process.

2. Endocrine disorders.

3. Overwork, poor sleep, bad mood, etc.

In short, low lactate dehydrogenase is generally not very serious and can be restored through conditioning. However, if lactate dehydrogenase is too high, it should be taken seriously. Pulmonary infarction, pernicious anemia, shock and pleural effusion caused by tumor metastasis can cause elevated levels of lactate dehydrogenase.