How many neutrophils are normal and what is the function of neutrophils

In daily blood tests, people often encounter situations where the number of neutrophils is too high or too low. So what is the normal number of neutrophils? Most people don't know. In fact, the normal value of neutrophils is within a range, just like white blood cells and red blood cells, and it also changes with the growth of the human body.

1. What is the normal value of neutrophils?

Normal reference values ​​for neutrophils:

Reference value: 0.40～0.75 (40%～75%); (1.80～6.30)×109/L.

2. Significance of neutrophil monitoring

1. Increase

Acute and suppurative infections (furuncles, abscesses, pneumonia, appendicitis, erysipelas, sepsis, visceral perforation, scarlet fever, etc.), various poisonings (acidosis, uremia, lead poisoning, mercury poisoning, etc.), tissue damage, malignant tumors, acute massive bleeding, acute hemolysis, etc.

2. Reduce

It is seen in infectious diseases such as typhoid, paratyphoid, measles, influenza, chemotherapy, and radiotherapy. Certain blood diseases (plastic anemia, agranulocytosis, myelodysplastic syndrome), hypersplenism, autoimmune diseases, etc.

3. The role of neutrophils

Neutrophils play a very important role in the nonspecific cellular immune system of the blood. They are at the front line of the body's defense against microbial pathogens, especially against the invasion of purulent bacteria. When inflammation occurs, they are attracted to the site of inflammation by chemotactic substances. Because they obtain their energy through glycolysis, they are able to survive the hypoxic conditions of swelling and poor blood flow, where they form cytotoxic cells that damage the cell membranes of bacteria and nearby tissues.

Because neutrophils contain a large amount of lysosomal enzymes, they can break down bacteria and tissue fragments that have been engulfed into the cells. In this way, the invading bacteria are surrounded in a local area and eliminated, preventing the spread of pathogenic microorganisms in the body. When the neutrophils themselves disintegrate, the release of lysosomal enzymes can dissolve the surrounding tissue to form an abscess.

Neutrophils are one of the items in routine blood tests, but do you know how to read a routine blood test report? When patients receive their blood test results, they are usually confused. What do all these densely packed data mean? Especially when I see several rising or falling arrows, I feel even more frightened, not knowing whether the problem is serious.

Experts say that when doctors receive a blood test report, they usually look at three main data: white blood cell count (WBC), lymphocyte percentage and neutrophil percentage. The white blood cell count is commonly known as the blood picture, and the latter two are the classification of white blood cells. Therefore, the number of neutrophils needs attention.