Is aplastic anemia leukemia? It turns out to be like this

Is aplastic anemia leukemia? This problem has always troubled anemia patients. In fact, aplastic anemia and leukemia are not the same disease, but both of them are very harmful to human health, so we must not ignore them.

Aplastic anemia is not leukemia. Although both are blood diseases, there are huge differences between them. We must be able to distinguish the difference between the two.

Aplastic anemia and leukemia are two different diseases. Aplastic anemia means that the body's hematopoietic system cannot produce normal blood cells, while leukemia means that blood cells cannot be produced. Leukemia is a blood disease characterized by too many or too few white blood cells without normal functions, while other blood cells may be normal!

Symptoms of aplastic anemia

Aplastic anemia (AA) is a bone marrow hematopoietic failure disease, mainly manifested by low bone marrow hematopoietic function, pancytopenia and anemia, bleeding, and infection syndrome. In clinical practice, bone marrow puncture and bone marrow biopsy are used to diagnose aplastic anemia. Aplastic anemia rarely heals on its own, so once diagnosed, it should be treated actively.

Anemia is quite common in my life, but aplastic anemia is probably relatively rare. Many people don’t know much about this disease, or even know nothing about it.

Next, an expert will explain to you the clinical symptoms of aplastic anemia. After understanding the symptoms of aplastic anemia, you can detect the disease in time and receive early treatment, which is also very helpful for the treatment of aplastic anemia.

The symptoms of aplastic anemia include the following

1. Signs and symptoms of aplastic anemia

It is divided into two major categories: congenital and acquired, with acquired types accounting for the vast majority. Congenital aplastic anemia is very rare, and its main type is Fanconi anemia.

2. Clinical manifestations and symptoms of aplastic anemia

The main clinical manifestations of aplastic anemia are anemia, bleeding and infection. The severity of clinical manifestations depends on the degree of hemoglobin, leukocytes, and thrombocytopenia, and is also related to the clinical type. The symptoms often worsen progressively, with obvious symptoms such as pallor, fatigue, dizziness, palpitations and shortness of breath.

Infect

Most patients with aplastic anemia will have fever, and their body temperature will be above 38 degrees, and for some patients, the body temperature cannot be controlled from onset to death.

Respiratory tract infection is the most common, and others include digestive tract, urogenital tract and skin infections. The infecting bacteria are mainly Gram-negative bacilli, Staphylococcus aureus and fungi, often accompanied by sepsis.

3. Symptoms of acute aplastic anemia

The characteristics of acute aplastic anemia are rapid onset, rapid progression, and short course. Anemia is often not obvious in the early stage of the disease, but as the disease progresses, anemia progressively worsens, and there are often obvious symptoms such as fatigue, dizziness, and palpitations. Even with massive blood transfusions, anemia is difficult to improve.

Bleeding and infection are often the main symptoms at the onset of the disease. Bleeding occurs in almost every case, and the bleeding sites are widespread. In addition to surface bleeding such as the skin, mucous membranes (oral cavity, nasal cavity, gums, and conjunctiva), there is often bleeding in deep organs, such as blood in the stool, blood in the urine, vaginal bleeding, fundus bleeding, and intracranial hemorrhage, the latter of which often endangers the patient's life.

More than half of the cases are infected at the onset, with oropharyngeal infection, pneumonia, skin furuncle, intestinal infection, and urinary tract infection being the most common. In severe cases, sepsis may occur. Infection often worsens bleeding and often leads to death.

4. Symptoms of chronic aplastic anemia

The characteristics of chronic aplastic anemia are slow onset, slow progression and long course. Anemia is the first and main manifestation. Blood transfusion can improve anemia symptoms such as fatigue, dizziness, and palpitations. Bleeding is generally mild, mostly superficial bleeding such as skin and mucous membranes, and deep bleeding is very rare.

During the course of the disease, there may be mild infections and fever, most of which are respiratory infections and are easier to control. If the infection is severe and the high fever persists, it often leads to worsening bone marrow failure and turns into severe aplastic anemia.

Bleeding

All of them had varying degrees of skin, mucous membrane and internal organ bleeding. Skin bleeding manifests as bleeding spots or large ecchymosis, and small blood blisters in the oral mucosa; there may be epistaxis, gingival bleeding, and conjunctival bleeding. All organs can bleed, but only bleeding from organs that open to the outside can be detected clinically.

Clinically, symptoms include vomiting blood, blood in the stool, blood in the urine, vaginal bleeding in women, followed by fundus hemorrhage and intracranial hemorrhage, the latter of which often endangers the patient's life. The number of bleeding sites increases from a few to internal organs, often heralding more serious bleeding.