If you are diagnosed with mild liver fibrosis, then you can be optimistic that your condition is relatively mild and it is discovered in time so there is a great chance that it can be cured. However, from a side point of view, mild liver fibrosis also requires active cooperation with treatment and attention to diet. For mild liver fibrosis, you can consider using Chinese medicine to treat it and help improve liver function problems. For the treatment of mild liver fibrosis, etiological treatment is the primary countermeasure, such as antiviral treatment, alcohol abstinence, etc., which can reduce the continuous damage to the liver and reduce the progression of liver fibrosis. However, etiological and anti-inflammatory treatments cannot equal or replace anti-fibrotic treatments targeting extracellular matrix metabolism and hepatic stellate cell activation. Current treatments cannot completely eliminate the cause of the disease. For example, they cannot completely eliminate the hepatitis B virus. However, a small amount of residual virus can still stimulate the formation of liver fibrosis by stimulating the immune system to damage liver cells. There is no term for fibrosis in traditional Chinese medicine, but some diseases related to connective tissue hyperplasia have the characteristics of blood stasis or accumulation of masses described in traditional Chinese medicine. Traditional Chinese medicine believes that the fundamental pathogenesis of mild liver fibrosis is the decline of the body's health and the prevalence of evil, with heat not yet completely eliminated; it is mainly caused by blood stasis, and the pathological manifestation is the formation of liver fibrosis. Modern medical research shows that Chinese medicine for promoting blood circulation and removing blood stasis has anti-liver fibrosis effect. The research on Chinese medicine for anti-liver fibrosis is as follows: 1. Single Chinese medicine: Experiments and clinical trials have shown that Chinese medicines with anti-fibrosis effects include Salvia miltiorrhiza, peach kernel, Cordyceps sinensis, tetrandrine A, Angelica sinensis, Astragalus, Poria, Bupleurum, Safflower, Licorice, Sophora flavescens, and Zedoariae rhizome. 2. Compound Chinese medicine: The mechanism of liver fibrosis in patients with chronic HBV infection is complex. According to TCM syndrome differentiation, in addition to blood stasis, there are also damp-heat, liver depression, spleen deficiency, yin deficiency and other syndromes. Late-stage patients also have symptoms of qi stagnation, dampness, heat accumulation, phlegm obstruction and deficiency of the body. A single medicine is difficult to achieve a comprehensive therapeutic effect. While promoting blood circulation and removing blood stasis, it also takes into account removing evil, strengthening the body, replenishing deficiency, strengthening the spleen, invigorating qi and tonifying the kidney. Long-term use of blood circulation and blood stasis drugs can inhibit the development of liver fibrosis and even reverse the established cirrhosis. It can significantly improve mild liver fibrosis in terms of histopathology, but currently no Western medicine has such therapeutic effect. Clinically, Western antiviral drugs can effectively inhibit viral replication and promote long-term remission in patients with liver disease, but HBeAg or even HBsAg serum conversion to negative does not mean cure; the use of simple antiviral treatment for chronic HBV infection cannot achieve the ultimate goal; in addition, the IFN-γ response rate is low, the adverse reactions are large, and the disease is prone to rapid relapse after discontinuation of nucleotide analogs, which are all shortcomings of antiviral treatment. Traditional Chinese medicine pays attention to the group view and treatment based on syndrome differentiation. Its main advantage is anti-fibrosis and group treatment mainly based on promoting blood circulation and removing blood stasis. It is unique in improving efficacy, reducing recurrence or improving symptoms. In the clinical process, the combination of Chinese and Western medicine, taking advantage of their respective strengths and avoiding their respective weaknesses, can achieve the best therapeutic effect for patients with hepatitis B liver fibrosis. |
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