Symptoms of Pseudomonas infection

Pseudomonas infection is often caused by a decrease in human body resistance, which leads to an infection of the corresponding parts of the body. Common clinical symptoms include sepsis, purulent meningitis, respiratory tract infection, digestive tract infection, etc.

1. Causes

Pseudomonas aeruginosa (Pseudomonas aeruginosa) is a common conditional pathogen among Pseudomonas. When the human body's resistance is reduced, it can enter the body and cause infections in corresponding parts of the body, such as burn surfaces, respiratory tract, urinary tract, central nervous system, cornea, and other infections, as well as sepsis. Because Pseudomonas aeruginosa is naturally resistant to most antibiotics, it is difficult to treat. Currently, anti-Pseudomonas aeruginosa synthetic penicillins and third-generation cephalosporins can be used for clinical treatment. Pseudomonas glanders (Bacillus mallei) and Pseudomonas pseudomallei (Bacillus pseudomallei) occasionally cause disease in humans. Burkholderia pseudomallei invades the human body through skin wounds, conjunctiva or respiratory tract, while Burkholderia pseudomallei infects the human body through direct contact, respiratory tract, digestive tract or insect bites. The clinical manifestations of the two are similar, and both can cause acute lung infection and localized infection in multiple parts and organs of the body. There is a lack of effective treatment for glanders, while melioidosis can be treated with tetracycline, chloramphenicol, etc. Both can provide more lasting immunity after the disease.

2. Clinical manifestations

1. Pseudomonas aeruginosa infection

Symptoms of infection appear in various systems and parts, such as infections of the burn surface, respiratory tract, urinary tract, central nervous system, cornea, etc.

(1) Sepsis is manifested by fever, toxic shock, disseminated intravascular coagulation, and central gangrenous pustular rash.

(2) Symptoms of purulent meningitis include high fever, vomiting, refusal to eat, crying and restlessness, and even convulsions.

(3) The main pathological feature of respiratory tract infection is necrotic alveolar membrane changes. It may be complicated by abscess, empyema and bronchopleural fistula.

(4) There are three main types of clinical symptoms of endocarditis, namely systemic infection symptoms, cardiac symptoms, and embolism and vascular symptoms.

(5) Newborns with gastrointestinal infection may experience diarrhea, fever, vomiting, dehydration, and necrotizing enterocolitis. Perirectal abscesses may occur in leukopenic patients with cancer.

(6) When the wound surface is infected after a burn and there is a green or blue-green sticky secretion with a sweet and fishy smell, and when there is green pus with a sweet and fishy smell under the scab, it is mostly an infection with Pseudomonas aeruginosa. Necrotic spots may reappear on the infected granulation wound.

(7) Other infections: peritonitis and urinary tract infection, corneal ulcer infection, eye inflammation, otitis externa, brain abscess, bone, joint and skin infection.