Common symptoms of Keshan disease include dyspnea, pale complexion, dizziness, and nausea. Clinically, there are three types of Keshan disease: acute, chronic, and subacute. The most common is acute. Acute Keshan disease is more likely to occur in winter and the onset is also relatively rapid. : : : : : : : : : : : : : : : 2. The subacute type mostly occurs in children after weaning and in preschool children (2 to 5 years old), and is more common in summer and autumn. The onset is slow, and the main symptoms are often body edema, mental depression, loss of appetite, and dull complexion. Chronic heart failure often occurs about 1 week after the onset of symptoms. A few may develop cardiogenic shock. Physical examination can show facial and body edema, enlarged heart, increased heart rate, often gallop rhythm and congestive hepatomegaly. If the condition has not been relieved after 3 months of onset, it will turn into a chronic type. 3. The slow type develops slowly, and may develop gradually from the asymptomatic stage, or it may be a transition from other types. The main clinical manifestations are chronic congestive heart failure, with palpitations, dyspnea, edema, liver congestion, enlarged heart borders, weakened first heart sound, gallop rhythm and various arrhythmias, especially ventricular premature contractions and atrial fibrillation. There may be murmurs of relative mitral and tricuspid regurgitation, and pleural effusion, ascites and pericardial effusion as well as corresponding symptoms and signs may also occur. Complications of chronic heart failure such as pulmonary infarction may also occur. In addition, due to the detachment of thrombi attached to the heart wall, embolism of the brain, kidneys, spleen, mesentery, etc. may occur. During the course of chronic Keshan disease, if symptoms and signs of acute cardiogenic shock appear, it is called chronic acute attack. 4. The latent type is often asymptomatic, with good cardiac function compensation, but there may be slight enlargement of the heart border. The electrocardiogram may show premature ventricular contractions or complete right bundle branch block or ST-T changes. It may be a latent type when discovered, called the stable latent type, with a good prognosis; it may also be a transition from other types, called the unstable latent type, with a worse prognosis than the stable latent type. |
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