Where is the best place to treat rheumatoid disease?

Currently, the number of hospitals treating rheumatoid diseases is gradually increasing, but the treatment and nursing methods of many hospitals are obviously different, resulting in many people not knowing how to choose and not knowing which hospital can achieve the best treatment effect for their own diseases. A good hospital is the key to the treatment of rheumatoid arthritis, so where is the best place to treat rheumatoid arthritis?

(1) Nonsteroidal anti-inflammatory drugs (NSAIDs) have anti-inflammatory, analgesic and antipyretic effects and are the most commonly used drugs in the treatment of rheumatoid arthritis. They are suitable for patients at all stages, including the active stage. Commonly used drugs include diclofenac, nabumetone, meloxicam, celecoxib, etc.

(2) Antirheumatic drugs (DMARDs) are also called second-line drugs or slow-acting antirheumatic drugs. Commonly used ones include methotrexate, taken orally or intravenously; sulfasalazine, starting with a small dose and gradually increasing, as well as hydroxychloroquine, leflunomide, cyclosporine, auranofin, and total glucosides of white peony.

(3) Yunke, i.e. technetium [99Tc] methylene diphosphonate injection, is a non-excited isotope that has a rapid onset of action in the treatment of rheumatoid arthritis and relieves symptoms with minimal adverse reactions. Intravenous medication, 10 days as a course of treatment.

(4) Glucocorticoids are not the first choice for the treatment of rheumatoid arthritis. However, hormones can be used in the following four situations: ① Accompanied by rheumatoid vasculitis including multiple mononeuritis, rheumatoid pneumonitis and serositis, iritis, etc. ② Transitional treatment: In patients with severe rheumatoid arthritis, a small amount of hormones can be used to quickly relieve the condition. Once the condition is under control, the hormones should be reduced or slowly discontinued. ③ For patients who have not responded to regular slow-acting antirheumatic drugs, low-dose hormones can be added. ④ Local application such as intra-articular injection can effectively relieve joint inflammation. The general principle is short-term use of small doses (less than 10 mg/d).

(5) Biological agents: Currently, several biological agents have been approved for marketing in the treatment of rheumatoid arthritis and have achieved certain therapeutic effects, especially in the treatment of refractory rheumatoid arthritis. The application of several biological agents in rheumatoid arthritis: ① Infliximab, also known as TNF-α chimeric monoclonal antibody, has been shown in clinical trials to achieve satisfactory therapeutic effects in patients with rheumatoid arthritis who are unresponsive to methotrexate and other treatments. In recent years, emphasis has been placed on early application to achieve better results. Usage: Intravenous injection, 3 mg/kg, once at 0, 2, and 6 weeks, and then once every 8 weeks. Usually 3 to 6 times as a course of treatment. It needs to be used in combination with MTX to inhibit the production of anti-antibodies. ②Etanercept or the fusion protein of human recombinant TNF receptor p75 and IgG Fc segment. Etanercept and the fusion protein of human recombinant TNF receptor p75 and IgG Fc segment have definite efficacy in the treatment of rheumatoid arthritis and AS and are well tolerated. Currently, there are two commercial dosage forms of Enbrel and Yisaipu in China. ③Adalimumab is a fully humanized monoclonal antibody against TNF-. The recommended therapeutic dose is 40 mg, once every 2 weeks, subcutaneously injected. ④Tocilizumab, an IL-6 receptor antagonist, is mainly used for moderate to severe RA and may be effective for patients who have a poor response to TNF-α antagonists. The recommended dosage is 4-10 mg/kg, intravenous infusion, once every 4 weeks. ⑤ Anti-CD20 monoclonal antibody Rituximab has achieved satisfactory results in the treatment of rheumatoid arthritis. Rituximab can also be used in combination with cyclophosphamide or methotrexate.

(6) Herbal medicines: Currently, there are many herbal medicines used for rheumatoid arthritis, such as tripterygium wilfordii, total glycosides of white paeony, and sinomenine. Some drugs have certain efficacy in treating rheumatoid arthritis, but their mechanism of action needs further study.

Nowadays, many folk remedies can treat rheumatoid arthritis, but we must be cautious when choosing folk remedies. We cannot blindly use folk remedies to treat our own diseases, otherwise it will not only fail to treat our own diseases, but may even cause serious physical harm. It is best to choose a regular hospital for examination and then treat the disease.