What are the types of beta thalassemia

What are the types of beta thalassemia

If a child suffers from anemia, it will have a certain impact on the child's physical growth, especially when β-thalassemia occurs. Because the symptoms are not very obvious, parents often cannot discover it in time, which will only cause β-thalassemia to cause more serious harm to the child. To this end, this article will introduce the types and symptoms of β-thalassemia, hoping that parents can have a detailed understanding.

Pediatric experts point out that β-thalassemia in children is a type of blood pressure medical disease. If the condition is not very serious, it is not difficult to treat. However, if the disease lasts for a long time and is not treated in time, it will have a great impact on the patient's development. The clinical manifestations vary depending on whether the β gene defect produces heterozygotes or homozygotes. According to the severity of the disease, it can be divided into three types: mild, intermediate, and severe.

1. Beta thalassemia minor

The main manifestations are mild microcytic and hypochromic anemia. It is especially obvious in infancy, and may cause mild jaundice and splenomegaly.

2. Beta-thalassemia intermedia

Its clinical manifestations are between severe and mild, with the following characteristics: late onset age (usually 4 to 5 years old), jaundice may or may not be present, weak resistance to external infections, and mild bone changes. Mild or moderate hepatosplenomegaly. Moderate anemia, Hb 60-90g/L, life can be maintained with a small amount of blood transfusion or without blood transfusion; the red blood cell morphology in the peripheral blood smear is similar to that of severe anemia. The osmotic fragility of red blood cells decreases, the HbF content increases, and the HbA2 may be slightly high, normal, or decreased.

3. β-thalassemia major

Clinically, the child presents with chronic hemolytic anemia. It is a common type of thalassemia in my country.

You should now be very clear about the types of β-thalassemia. Parents and friends, please note that if the symptoms of β-thalassemia in children are more severe, it can easily cause the child to faint and have hepatosplenomegaly, which is extremely detrimental to the child's development. Therefore, I hope that parents and friends can help their children prevent β-thalassemia.

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