Leukemia is a type of malignant clonal disease of hematopoietic stem cells. According to the severity of onset, leukemia can be divided into acute and chronic leukemia. The differentiation of acute leukemia cells stagnates at an early stage, with primitive and early immature cells being the main components. The disease progresses rapidly and lasts for several months. Chronic leukemia cells are well differentiated, mainly composed of immature or mature cells, develop slowly, and the course of the disease is several years. Classified by the series of diseased cells, it includes the granulocyte, monocytic, erythroid, megakaryocytic cells of the myeloid system and the T and B cell lines of the lymphoid system. Clinically, leukemia is often divided into acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML, formerly known as acute non-lymphocytic leukemia), chronic myeloid leukemia, chronic lymphocytic leukemia, etc. Many people are very scared when they hear the word leukemia because leukemia is highly malignant. Once someone in the family is diagnosed with leukemia, it will bring great pain to the entire family. We must pay attention to details in our lives to keep leukemia away from us. According to research, long-term contact of too white toilet paper with skin may cause leukemia and cancer. Toilet paper that is too white may increase the risk of leukemia People cannot live without toilet paper every day. Toilet paper is mostly recycled paper. In order to beautify the appearance, most toilet papers are added with dyes, including fluorescent brighteners or talcum powder. The whiter the toilet paper, the more fluorescent brighteners or talcum powder may be added. These additives mostly contain the compound benzene; some poor quality toilet papers also contain formaldehyde. Long-term contact with skin of these substances may cause leukemia and cancer. What causes leukemia? 1. Virus: It has been confirmed that leukemia virus can be isolated from spontaneous leukemia tissues of animals such as chickens, mice, cats, cows and gibbons. This virus is a type C retrovirus. The study of viral etiology of human leukemia has a history of several decades, but so far only adult T-cell leukemia has been confirmed to be caused by LT cell leukemia virus-1 (HTLV-1). HTLV-1 is contagious and can be transmitted through sexual intercourse and blood transfusion, and can also be transmitted from mother to child through breast milk. 2. Radiation: Ionizing radiation is definitely effective in treating leukemia, and its effectiveness is related to the radiation dose and the irradiated area. A single high-dose or multiple low-dose exposures can cause leukemia. Whole body irradiation, especially bone marrow irradiation, can cause bone marrow suppression and immunosuppression. Chromosome breaks and abnormalities can still be observed several months after irradiation, and can then induce acute non-lymphocytic leukemia, acute lymphocytic leukemia and chronic myeloid leukemia. There is often a bone marrow transplant period before the onset of the disease, and the incubation period is about 2-16 years or less than one year. There is no definite evidence whether diagnostic irradiation can cause leukemia, but intrauterine irradiation of pregnant women can increase the risk of leukemia in their babies after birth. 3. Chemical substances and poisons: The pathogenic effect of benzene is relatively certain. The leukemias caused are mainly acute myeloid leukemia, erythroleukemia and chronic myeloid leukemia. Alkylating agents and cytotoxic drugs can cause secondary leukemia. Secondary leukemia caused by chemotherapy for tumors or connective tissue diseases is mainly a second tumor and non-lymphocytic leukemia, and there is often a period of pancytopenia before the onset of the disease. Drugs for treating psoriasis, such as ethodimorph, ethylenediamine, and dioxazine, are all chromosomal aberration-causing substances that can cause secondary leukemia, mainly acute promyelocytic leukemia, which usually occurs 1-7 years after taking the drugs. 4. Genetic factors: The onset of certain leukemias is related to genetic factors. If one of monozygotic twins has leukemia, the chance of the other one also having leukemia is 20%. A small number of leukemias are familial, and familial leukemia accounts for 7% of all leukemia cases. Congenital leukemia is also occasionally seen. Certain hereditary diseases are also often accompanied by a higher incidence of leukemia, including Down, Bloom, Klinefelter, Fanconi and Wiskott Aldrich syndromes. These hereditary diseases often have chromosomal aberrations and breaks. |
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