What are the typical symptoms of osteosarcoma

What are the typical symptoms of osteosarcoma?

1. Pain is an early symptom and may occur before the tumor appears. It is intermittent pain at first and gradually becomes continuous severe pain, especially at night. Malignant tumors cause pain earlier and more severely. There is often a history of local trauma, bone and joint tumors, hardness, tenderness, local temperature, venous dilation, and sometimes pulsation, pathological fractures, and gradual deterioration of overall health. Most patients have lung metastasis within one year.

2. It often occurs clinically in adolescents, with less cases in the mandible and more common cases in the maxilla, with a history of injury. The early symptoms are intermittent numbness and pain, which then turn into continuous severe pain and reflex pain; the tumor grows rapidly, destroying the alveolar bone and breaking through the jaw, causing loose and displaced teeth, facial deformity, and pathological fractures. X-rays show irregular injuries that expand from the inside to the outside in a lytic bone type; cortical bone damage replaces hyperplastic bone, and sunlight radiation arranges it into a bone type. A mixture of the above two types can also be seen clinically. In the late stage, serum calcium and alkaline phosphatase may increase, and the tumor is easily metastatic to the lungs along the blood vessels.

3. The course of the disease varies, from the onset of symptoms to medical treatment in a few days to several years, with an average of 3 to 4 months. The earliest clinical symptom is pain in the hair area around the knee joint, which is mainly hidden pain. It is persistent and worsens after activity. The pain is more obvious at night. A lump appears in the affected area, and the growth rate of the lump is usually calculated every month. When the lump increases significantly, the adjacent joints react with effusion, and the joint movement is limited. Early pain often occurs suddenly after a minor injury. The swelling starts out mild and then gradually worsens. It is eccentric fusiform swelling, and the hardness of the lump varies. Due to the different texture of the tumor, the osteolytic lesion is softer. The skin of the affected area is bright, the surface veins are dilated, and the skin temperature rises. If the tumor is large and adjacent joints are affected, it may affect joint function, and some patients metastasize to other parts.