In life, many people will have a high anion gap during serum examination. This situation usually occurs in diabetic patients. Diabetes has a lot to do with our kidneys. In the late stage of diabetes, it is likely to turn into uremia. Therefore, the anion gap is high, which is also a serious situation. So what should we do if the anion gap is high? The high anion interval refers to the difference between the total number of cations and anions measured in serum. It can differentiate between different types of metabolic acidosis. Clinical significance: Increased: seen in metabolic acidosis, diabetic ketoacidosis, uremia, etc. Metabolic acidosis with a normal anion gap, such as hyperchloremic metabolic acidosis. Normal range: 8~16mmol/L. Test description: refers to the difference between the total number of cations and anions measured in serum. It can differentiate between different types of metabolic acidosis. Clinical significance: Increased: seen in metabolic acidosis, diabetic ketoacidosis, uremia, etc. Metabolic acidosis with a normal anion gap, such as hyperchloremic metabolic acidosis. Decreased: seen in hypoproteinemia, etc. 1. High blood uric acid: kidney damage, excessive intake of purine-containing foods. Plantago seed and Centella asiatica can lower uric acid. Eat less thick broth, animal offal, thick chicken soup, sardines, dried fish, anchovies, oysters and other foods high in purine. 2. High blood phosphorus: reduced phosphorus excretion by the kidneys, renal failure, excessive intake of phosphorus-containing foods Supplement calcium, adjust the calcium-phosphorus ratio, daily phosphorus intake should not exceed the recommended amount of 700 mg, protect the kidneys, make phosphorus excretion normal, and eat whole grains that contain phosphorus but are not easily absorbed and utilized. 3. Low anion gap: Clinical manifestation is hypoalbuminemia, caused by intestinal loss, cirrhosis, splenomegaly, renal failure, insufficient liver synthesis, lymphatic obstruction, and hyperthyroidism. Supplement high-quality protein, Panax notoginseng and Salvia miltiorrhiza can soften the liver and spleen, while Prunella vulgaris and Plantain chinensis can promote lymphatic transformation. 4. High aspartate aminotransferase and alanine aminotransferase: fatigue, greasy food, drugs, myocardial infarction, and cirrhosis. Schisandra chinensis can lower transaminase, so eat less greasy and fatty meat. 5. High lactate dehydrogenase: myocardial infarction, muscular dystrophy, myocarditis, hemolytic anemia, cirrhosis This is a glycolytic enzyme. Raw Rehmannia, Scrophularia, Chinese Yam, Polygonatum, Astragalus, and Atractylodes can lower blood sugar. 6. High hydroxybutyrate dehydrogenase: excessive destruction of red blood cells, myocardial infarction. Astragalus and jujube nourish the blood. |
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