What are the symptoms of intracranial neurofibroma

Intracranial neurofibroma is an uncommon disease. It is very harmful in itself and can easily cause other complications. Intracranial neurofibroma is also hereditary and is a dominant gene genetic disease. It has very obvious symptoms. The external symptoms are mainly reflected in the skin, eyes and bones, and the internal symptoms are mainly nerve damage. The following is a detailed introduction to the symptoms of intracranial neurofibroma.

The first is skin symptoms. Almost all patients with intracranial neurofibroma will show obvious café au lait spots when they are just born. The size and shape of these spots are irregular, the edges of the spots are not very regular, and the spots will not protrude from the surface of the skin. They like to exist in easily exposed skin locations; the size and number of spots have a high diagnostic basis. Generally, there are more than six spots with an area larger than five millimeters before puberty. After puberty, the area of ​​the spots will rapidly increase and will change to more than 15 millimeters. Freckles on the whole body and armpits are also one of the characteristics. Skin fibroma is very similar to fibrous soft tumor. If the disease occurs during childhood, the spots are mainly distributed on the trunk and face, and are also common on the limbs. Most of the spots are pink, and there is no regularity in the number, but the size of the spots is maintained at the size of mung beans and sesame seeds, and the texture feels very soft.

The second is neurological symptoms. Only about half of the patients have neurological symptoms, mainly because the tumor compresses the central and peripheral nerves, and may also be caused by glial cell proliferation, vascular proliferation and bone deformity. Intraspinal tumors can cause single or multiple neurofibromas in each part of the spinal cord. They can merge to cause spinal deformity, expansion, and even symptoms of syringomyelia; peripheral nerve tumors can also affect nearby nerve tissues. When the intracranial neurofibroma suddenly increases in size, it will feel obvious pain.

The third is eye symptoms. Fibromas or plexiform neurofibromas can be seen on the upper eyelids, lumps and exophthalmos can be palpated in the eye sockets, and slit light can reveal small orange-yellow round nodules on the iris, which can increase with age and are unique to intracranial neurofibromas. The fundus of the patient's eyes will be obviously grayish white, and the optic disc will bulge out severely; severe cases of intracranial neurofibromas can cause exophthalmos and blindness.

As a genetic disease, intracranial neurofibroma has a low incidence rate, but if it is not controlled in time, it will show obvious symptoms. The significant features of the skin and eyes will affect the patient's appearance and cause psychological harm to the patient. Although the neurological symptoms cannot be seen from the outside, the patient will also feel pain, and the symptoms are very characteristic. After discovering that you have intracranial neurofibroma, you should go for regular examinations and treatment to control the condition.