Fever: Liver cancer is prone to cancer fever, which is often intermittent, without chills or shivering, and lasts for a long time. Occasionally, there is a persistent high fever without obvious symptoms of septicemia. This type of cancer fever is sensitive to antipyretics such as indomethacin, naproxen, and corticosteroids, but the fever will recur after stopping the drug. It is easy to misdiagnose as tuberculosis, typhoid infection, connective tissue disease, etc., thus delaying the correct diagnosis. The mechanism of cancer fever may be due to pyrogens or tumor necrosis factors produced by the cancer tissue itself or infiltrating leukocytes. However, infection must also be excluded for diagnosis. Diarrhea: Some liver cancer patients have diarrhea as the main digestive tract symptom, which is easily misdiagnosed as chronic enteritis or malabsorption syndrome. Diarrhea can also be the first symptom of liver cancer. According to statistics, among 3,254 liver cancer patients, 5.8% had diarrhea as the first symptom. Bone pain: It is caused by liver cancer bone metastasis, which can be single or multiple, often involving vertebrae, ribs, long bones of limbs, etc. It is worth noting that bone pain can be the first symptom of patients with primary liver cancer and is often misdiagnosed as other bone and joint diseases. The incidence of liver cancer bone pain is 3% to 12%, but autopsy finds that the incidence of bone metastasis can reach 20%. Cirrhosis: Primary liver cancer often occurs on the basis of cirrhosis. According to statistics, at least 80% of liver cancer is accompanied by cirrhosis, and about 15% to 75% of liver cancer is eventually caused by cirrhosis. Therefore, patients with cirrhosis, especially those infected with hepatitis B and hepatitis C viruses, should be highly vigilant about the occurrence of liver cancer and undergo relevant examinations regularly. |
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