What are the causes of fibroids

Fibroma is a benign tumor in the dermis caused by focal proliferation of fibroblasts or histiocytes. The disease can occur at any age, but is more common in young and middle-aged people, and more common in women than in men. Once it occurs, it will cause great harm to the patient's physical and mental health. Therefore, it is necessary to understand the cause of the disease in time in order to provide treatment and prevention. So, what are the causes of fibroma?

1. Cause: It originates from fibroid ectodermal tumors and is a type of poorly differentiated schwannoma. It can appear alone or as part of the systemic symptoms of Recklin-Chausen's disease. The latter is often accompanied by café-lait-pigmentation on the skin. It is a congenital malformation that is familial. Patients are relatively young and the disease progresses slowly.

2. Pathology: This tumor has no capsule, and even if it has one, it is incomplete. There is proliferation of various components of nerve tissue in the tumor, among which the proliferation of nerve sheath cells is the most obvious. In addition to a large amount of fibrous tissue proliferation, there are also blood vessels of varying sizes and thick nerves in the form of cords. The difference from nerve sheath tumor under the microscope is that there is no complete capsule and the tumor cells are not arranged in a fence-like manner.

Fibromatosis is a common genetic disease with an incidence rate of about 1/3000-1/2500 in the population, so it is estimated that there are 300,000 patients in China. About 50% of patients have a positive family history. This is an autosomal dominant genetic disease with a high penetrance. Among the existing patients, about half are inherited from the family and have a clear family history; the rest of the patients have no family history of inheritance, but the root cause of the disease lies in gene mutations and may be inherited from then on. This disease caused by genetic abnormalities affects multiple systems of the body.

The above content is what the experts introduced to us about the causes of fibroids. I hope that patients can understand it well. Fibroids are a common type of benign tumors. We must first understand the causes of fibroids before we can do a good job of prevention and fundamentally prevent the occurrence of the disease.