Is small cell lung cancer related to genetics?

Is small cell lung cancer related to heredity? Many people have never heard of this disease, but the elders who have this disease are worried that it will be passed on to the next generation. I wonder if it is hereditary? So, today we will learn whether small cell lung cancer is related to heredity!

It is generally believed that small cell lung cancer originates from Kulchitsky cells (argentophilic cells) in the bronchial mucosa or glandular epithelium and belongs to APUD (amine precursor uptake decarboxylation) tumors. Some people also believe that it originates from stem cells in the bronchial mucosal epithelium that can differentiate into neuroendocrine. Small cell lung cancer is the least differentiated and most malignant type of lung cancer. It often occurs in the central part of the lung, grows rapidly, and metastasizes early. Under a light microscope, cancer cells are small and short spindle-shaped or lymphocyte-like, with little cytoplasm and a naked nucleus-like shape. Cancer cells are densely arranged in groups, separated by connective tissue, and sometimes cancer cells are arranged in groups around small blood vessels. Moreover, small cell lung cancer is not inherited.

There are three levels of prevention for small cell lung cancer:

Primary prevention is for healthy people, mainly including not smoking and staying away from secondhand smoke pollution. Try to avoid outdoor air pollution and kitchen fumes. Choose environmentally friendly decoration materials. Eat a balanced diet, eat more grains, vegetables and fruits. Maintain an optimistic and positive attitude towards life and improve psychological adaptability.

Secondary prevention, early diagnosis and early treatment are aimed at high-risk groups, mainly long-term smokers over 40 years old, smokers for more than 20 years, smokers under 20 years old who start smoking and smoke more than 20 cigarettes a day, people who are often exposed to coal smoke, coal tar and oil smoke, people who are exposed to excessive radiation (miners, etc.), people with chronic cough, blood in sputum and family history of lung cancer. It is best for high-risk groups to have regular comprehensive physical examinations every year, and CT examinations if conditions permit. If symptoms such as irritating cough, bloody sputum and hemoptysis occur, they should go to the hospital for treatment in time.

The tertiary prevention is rehabilitation prevention. Lung cancer patients should follow the doctor's advice and go to the hospital for regular checkups.