What is the best medicine for small cell lung cancer

Small cell lung cancer is a type of cancer. Now more and more people are suffering from this disease. It is caused by lesions in the lungs, which make the patient's lungs unable to breathe normally. Suffering from small cell cancer is not a terrible thing. We must first face it with an optimistic attitude, and then we must actively participate in the treatment. So what is the best medicine for small cell lung cancer? Let's learn about it together.

1. Anti-angiogenic signaling pathway

Vascular endothelial growth factor (VEGF) is highly expressed in 80% of SCLC. Anti-angiogenic drugs for the treatment of SCLC may play a role by changing the tumor microenvironment, preventing the growth of micrometastases, and through long-term maintenance treatment.

2. Growth factor receptor inhibitors

Growth factor signaling pathway inhibitors, such as erlotinib and gefitinib, are very effective for lung adenocarcinoma with EGFR sensitive mutations. EGFR mutations are rare in SCLC patients, but in patients with complex SCLC, the literature reports that the rate ranges from 2.4% to 4%, with EXON-19Del being relatively common and sensitive to EGFR-TKI treatment, suggesting that EGFR mutation testing may be needed to guide clinical treatment for complex SCLC. There is currently no relevant clinical research data on Erbitux, a monoclonal antibody targeting EGFR, in SCLC.

3. Pro-apoptotic agents

Promoting tumor cell apoptosis may be another new treatment strategy for SCLC, mainly including BCL-2 inhibitors and histone deacetylation.

4. Vinca alkaloids: Vincristine, vinblastine, and vinblastine amide, which are commonly used in small cell lung disease, are effective at 35%, 40%, and 30% respectively. Among them, vincristine and cyclophosphamide are still the first-line drugs and are economical and effective.

5. Others: New anti-disease drugs introduced in the 1990s, such as Taxol, Gemcitabine, Topotecan, and Irinotecan, are all effective at more than 30% per drug, but they are expensive.

The above are the best drugs for treating small cell lung cancer. Everyone should learn more about them.