How to treat advanced gastric cancer

How to treat advanced gastric cancer? When gastric cancer has reached the advanced stage, many people may fall into despair. Some of them give up treatment and wait for death to come. Little do they know that "giving up treatment" itself is like death. Patients are sentencing themselves to death. In fact, there are also treatments for advanced stage. Medical staff have never given up on researching treatments for advanced gastric cancer. Patients should not complain about themselves. So how to treat advanced gastric cancer?

1. Surgical treatment

(1) The principle of radical surgery is to remove part or all of the stomach including the cancer lesion and the possibly infiltrated stomach wall in one piece, remove the lymph nodes around the stomach in one piece according to the clinical staging criteria, and reconstruct the digestive tract.

(2) Palliative surgery: When the primary lesion cannot be removed, surgery is performed to alleviate symptoms caused by complications such as obstruction, perforation, and bleeding, such as gastrojejunostomy, jejunostomy, and perforation repair.

2. Chemotherapy

It is used before, during and after radical surgery to prolong survival. Patients with advanced gastric cancer can use appropriate chemotherapy to slow down the growth of the tumor, improve symptoms, and have certain short-term effects. In principle, adjuvant chemotherapy is not necessary after radical surgery for early gastric cancer. Adjuvant chemotherapy should be performed in the following cases: high malignancy of pathological type; cancer area greater than 5 cm; multiple cancer lesions; age under 40 years old. Chemotherapy is required for patients with advanced gastric cancer who have recurred after radical surgery, palliative surgery, or radical surgery.

Common chemotherapy administration routes for gastric cancer include oral administration, intravenous administration, intraperitoneal administration, and arterial catheterization regional perfusion administration. Common oral chemotherapy drugs include tegafur, eufodine, flutolan, etc. Common intravenous chemotherapy drugs include fluorouracil, mitomycin, cisplatin, doxorubicin, etoposide, and calcium leucovorin. In recent years, new chemotherapy drugs such as paclitaxel, oxaliplatin, topoisomerase inhibitors, and Xeloda have been used for gastric cancer.

3. Other treatments

Including radiotherapy, hyperthermia, immunotherapy, traditional Chinese medicine treatment, etc. Immunotherapy for gastric cancer includes non-specific biological response modifiers such as BCG, Lentinan, etc.; cytokines such as interleukin, interferon, tumor necrosis factor, etc.; and adoptive immunotherapy such as lymphocyte activated killer cells (LAK), tumor infiltrating lymphocytes (TIL) and other clinical applications. Anti-angiogenesis gene is a gene therapy method that has been studied more and may play a role in the treatment of gastric cancer.

The prognosis of gastric cancer is related to its pathological stage, location, tissue type, biological behavior and treatment measures. Early gastric cancer has a better prognosis after treatment. Cardiac cancer and proximal gastric cancer in the upper 1/3 of the stomach have a worse prognosis than gastric body and distal gastric cancer. However, patients must face the treatment of the disease positively and optimistically and have confidence in themselves to defeat the disease as soon as possible.