Causes of recurrent glioma

Gliomas, as the name suggests, are prone to recurrence after treatment. More than 60% of patients who undergo surgical resection will experience a secondary recurrence. Many patients are confused about this. Tumors that have been surgically removed will still recur after radiotherapy and chemotherapy. What is the reason for this? Let's understand the reasons for the recurrence of gliomas.

Experts explain: Glioma is the most common primary intracranial tumor. The World Health Organization is the most authoritative one at present, dividing it into four levels. The higher the level, the higher the malignancy. Moreover, glioma occurs in the central nervous system, and its malignant progression is often accompanied by damage to multiple functions such as movement, language, and sensation, and the quality of life and survival will be significantly reduced in the future.

1. Bad living habits: such as partiality to certain foods, drinking, smoking, etc., these factors can indirectly cause the occurrence of glioma;

2. Genetic factors: These are the most important innate factors. This does not mean that gliomas are hereditary, but rather that due to the presence of some genetic factors, especially defects in certain tumor suppressor genes, the likelihood of developing gliomas in these people will increase under the influence of exogenous factors.

3. Ionizing radiation: Long-term exposure to radiation, such as X-rays, γ-rays, nuclear radiation, etc., will increase the chance of developing brain glioma;

4. Air pollution: The risk of brain tumors in workers who work in air-polluted environments for a long time is significantly increased, and the incidence of tumors in their children is also higher than that in other children. These occupations are mainly related to papermaking, milling, handicrafts, printing, chemicals, oil refining and metal smelting, mainly because there are a lot of hydrocarbon compounds in the air, and air polluted by pesticides is also included.

In short, the reason why malignant glioma recurs is mainly due to its invasive growth characteristics. At present, surgery, radiotherapy and chemotherapy cannot eradicate residual, latent tumor cells. Even so, once patients find abnormalities, they still need to go to relevant specialist hospitals for examination and treatment in time. At the same time, we believe that in time, humans will have more effective measures to prevent recurrence.