Causes of pituitary tumors

The incidence of pituitary tumors has a tendency to gradually increase. The causes of pituitary tumors are very complex. Currently, the number of men suffering from pituitary tumors is higher than that of women, and the number of manual laborers suffering from the disease is higher than that of mental laborers. Studies have found that it may also be related to some genetic factors. So, what are the causes of pituitary tumors? Let's take a look.

Pituitary tumors are a very common disease, with about 1 case in 100,000 people. In recent years, there has been an increasing trend, especially in women of childbearing age. There are many causes of pituitary tumors, and targeted understanding will help with active treatment in the later stages.

The cause of pituitary tumors is that hypothalamic polypeptide hormones promote the proliferation of pituitary cells. For example, after the GHRH gene is transplanted, it can cause the proliferation of rat GH cells and then develop into a true pituitary tumor. The lack of inhibitory factors can also promote tumor occurrence. For example, ACTH adenoma can occur in patients with primary adrenal cortex insufficiency. The cause of pituitary tumors is a tumor that occurs on the pituitary gland, which is usually called a pituitary adenoma. It is one of the common neuroendocrine tumors, accounting for about 10-15% of central nervous system tumors. The vast majority of pituitary adenomas are benign tumors.

There are two theories about the etiology of pituitary tumors: one is the hypothalamic origin theory; the other is the pituitary origin theory. Based on the clonal analysis of tumor cells, it is currently believed that most pituitary tumors are caused by monoclonal mutations of somatic cells, that is, the tumor is caused by mutations of pituitary cells. Pituitary tumors can be divided into pituitary tumors with hormone secretion function and non-functional pituitary tumors. The former mainly includes: pituitary growth hormone adenoma, pituitary prolactin adenoma, pituitary ACTH adenoma (also known as Cushing's disease), pituitary TSH adenoma, pituitary gonadotropin adenoma, etc. Since the early symptoms of non-functional pituitary adenoma are not obvious, most of them are diagnosed with symptoms of optic chiasm compression such as decreased vision and visual field defects when they are discovered. At this time, most of the tumors are large adenomas or giant adenomas.

The above are the causes of pituitary tumors. I have introduced these to you and hope that they will be helpful to you. In life, you should learn more about pituitary tumors so that you can effectively prevent pituitary tumors, detect pituitary tumors early, and avoid causing greater harm to your body.