Causes of osteosarcoma

Causes of osteosarcoma

As we all know, osteosarcoma is difficult to cure and prone to recurrence, so what is the cause of osteosarcoma? Osteosarcoma, also known as osteogenic sarcoma, is a malignant bone tumor that develops from the mesenchymal cell line. Because the tumor directly or indirectly forms tumor bone-like tissue and bone tissue during the cartilage stage, the tumor grows rapidly. After understanding osteosarcoma, let's learn about the causes of osteosarcoma.

The cause of osteosarcoma is related to the following factors.

1. Osteosarcoma is the most common type of bone malignancy. It develops from the mesenchymal cell line. The rapid growth of the tumor is due to the direct or indirect formation of tumor bone-like tissue and bone tissue during the cartilage stage. Under the influence of external factors (such as viruses), the weight-bearing bones of the lower limbs cause cell mutations, which may be related to the formation of osteosarcoma.

2. Traumatic stimulation. Since the patient suffers from external traumatic injuries and is not treated in time, it is easy to cause lesions in the long run.

3. Typical osteosarcomas originate from the bone. Another completely different type of osteosarcoma is the osteosarcoma that is parallel to the bone cortex and originates from the periosteum and nearby connective tissue. The latter is less common and has a slightly better prognosis.

4. Radioactive isotope radium. During the process of bone growth, the tumor also develops rapidly outward, invading the Hastelloy system in the cortical bone and causing vascular nutritional disorders, and the cortical bone is then destroyed.

5. It is also related to heredity, exposure to radioactive substances, viral infection, etc. It can also be secondary to osteitis deformans and fibrous dysplasia of bone. Some cases are caused by the malignant transformation of other benign tumors.

The above are the main reasons for the formation of osteosarcoma that we would like to introduce to you. We hope that it will be helpful for you to prevent osteosarcoma.

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