Late recurrence of endometrial cancer

How long does it take for endometrial cancer to recur? There are many ways to treat endometrial cancer, but surgery cannot completely eradicate cancer cells. After surgery, the body's ability to fight cancer decreases, making it more likely to recur and spread. So how long does endometrial cancer recur? Here is our detailed introduction, hoping it will be helpful to everyone.

The cause of recurrence of endometrial cancer is still unknown, but its risk factors have long been noticed. Experts say: "Obesity, diabetes, and high blood pressure are all related to endometrial cancer. Especially when these three conditions exist at the same time, the risk of endometrial cancer is higher than that of normal people. Therefore, obesity, diabetes, and high blood pressure are traditionally called the triad of endometrial cancer. Clinically, there are more fat patients and relatively fewer thin people, and this is closely related to the daily high-fat diet. Infertility patients, polycystic ovary syndrome patients, certain ovarian tumor patients, and family genetic tendencies are all high-risk groups for endometrial cancer." Family history, those with a family history of ovarian cancer, colon cancer, or breast cancer are more likely to develop endometrial cancer than those without a family history. Those with better economic conditions, especially those with a high-fat diet, are also high-risk groups for endometrial cancer. In the United States, some people have conducted a controlled study and found that the incidence of endometrial cancer in women with high cultural level and high economic income is significantly higher than that in women with low cultural level and low economic income. However, some people believe that it may be because the former are more likely to use estrogen replacement therapy for a long time and are obese. Generally speaking, the incidence of endometrial cancer is higher in economically developed countries than in underdeveloped countries, and higher in cities than in rural areas.

Obesity, hypertension, and diabetes are generally referred to as the endometrial cancer triad. In fact, hypertension and diabetes have no direct relationship with endometrial cancer. Obesity, hypertension, and diabetes may all be the result of hypothalamic-pituitary-adrenal dysfunction or metabolic abnormalities. At the same time, pituitary gonadotropin function may also be abnormal, resulting in anovulation and no progesterone secretion, which causes the endometrium to be continuously stimulated by estrogen for a long time. Some people believe that premenopausal obesity, especially those who have been obese since young, is also a high-risk factor for endometrial cancer, because obese people are often accompanied by a relative lack of progesterone secretion in the luteal phase, or at the same time, they are accompanied by irregular menstruation or even amenorrhea. Endometrial cancer can be divided into estrogen-dependent (type I) and non-estrogen-dependent (type II) according to its pathogenesis and biological behavior characteristics.

Most estrogen-dependent endometrial cancers are endometrioid carcinomas, and a small number are mucinous adenocarcinomas; non-estrogen-dependent endometrial cancers include serous carcinomas, clear cell carcinomas, etc. Warm reminder: How long does it take for endometrial cancer to recur? This question cannot be answered specifically. It depends on the patient's physical condition and whether their living habits are normal. There are many reasons for recurrence, and people need to understand them in time to better prevent them.