Possibility of curing endometrial cancer

Possibility of curing endometrial cancer

The possibility of curing endometrial cancer depends on the patient's condition. If it is in the early stage, it is relatively easy to treat. If it is in the middle or late stage, the main treatment is to prolong life. Patients should take treatment measures according to their condition to avoid causing harm. Generally speaking, the earlier the cancer is discovered and treated, the higher the cure rate. The second thing is whether the treatment method chosen is correct.

Endometrial cancer is a malignant tumor originating from the endometrial glands, also known as uterine body cancer. It is one of the common gynecological malignancies, which is prone to occur during menopause and postmenopause, and is more common in unmarried, under-fertilized, obese women with hypertension and diabetes. The onset of endometrial cancer is generally believed to be related to estrogen. The most common pathological type is adenocarcinoma, which generally develops slowly and is mainly manifested by irregular vaginal bleeding and increased discharge. Various pathways include direct spread or lymphatic and blood circulation.

The treatment lasts for half a year, with surgery as the main treatment, and radiotherapy, chemotherapy, progesterone anti-estrogen and other drugs as the auxiliary treatment. If it can be found early, diagnosed early, and treated correctly early, the effect will be better. Recurrence is mostly within 3 to 5 years, and there is a long-term recurrence, so long-term follow-up is required. Can endometrial cancer be completely cured? This question is closely related to the patient's own condition and the choice of treatment method. Surgical treatment is the first choice for uterine cancer that has not metastasized or spread.

The first choice of treatment for early endometrial cancer is total hysterectomy, including removal of the uterus, cervix, ovaries and fallopian tubes. Extensive surgical procedures are sufficient to cure early uterine cancer and prevent recurrence to the greatest extent possible. If the cancer has spread beyond the uterus, radiotherapy is added after surgery to eliminate residual cancer cells. When the cancer has not spread and the lesion is large, some doctors also recommend radiotherapy. Treatment mainly includes surgery, radiotherapy and drug therapy. The treatment plan should be formulated according to the patient's overall condition, the extent of the tumor and the degree of malignancy. Surgery is the main treatment in the early stage, and comprehensive treatment such as radiation, surgery and drugs is used in the late stage.

1. Surgical treatment Stage I: Patients should undergo extrafascial total hysterectomy plus bilateral salpingectomy or sub-extensive hysterectomy, pelvic and para-aortic lymph node dissection or sampling. Stage II: Extensive hysterectomy, bilateral salpingectomy, pelvic and para-aortic lymph node dissection should be performed. Stage III: Comprehensive treatment is the main treatment, and radiotherapy is often the first choice, or surgery is performed after the cancer lesions are reduced by radiotherapy; postoperative radiotherapy, chemotherapy, and hormone comprehensive treatment are supplemented. For those with distant metastasis, radiological interventional treatment can be performed as appropriate. Stage IV: Progesterone therapy and (or) chemotherapy.

2. Radiotherapy Simple radiotherapy: Suitable for patients in advanced stages or those who cannot tolerate surgery. It includes intracavitary and extracorporeal irradiation.

(1) Intrauterine irradiation: Radiotherapy to the uterine cavity and vaginal vault. (2) External irradiation: The irradiated area includes the tumor and pelvic infiltration.

3. Surgery plus radiotherapy (1) Preoperative radiotherapy: Reduces vaginal vault recurrence, shrinks or eradicates regional lymph node metastasis, and can also reduce the size of the tumor, inactivates cancer cells, reduces intraoperative spread and bleeding, and reduces the possibility of postoperative recurrence and distant metastasis, thus improving the surgical cure rate. Generally, intracavitary radiotherapy is performed 7 to 10 days after intracavitary radiotherapy, and preoperative external irradiation is performed 6 weeks after radiotherapy. (2) Postoperative radiotherapy: Supplements the deficiencies of surgery. If postoperative pathology confirms that cancer cells have involved the cervix, the cancer has invaded more than 1/2 of the uterine myometrium. Poor cell differentiation. The lesion extends beyond the uterus, and the pathological examination shows adenosquamous carcinoma/clear cell carcinoma/papillary adenocarcinoma, and the paracervical lymph nodes are positive. External irradiation should be supplemented after surgery. Intracavitary radiotherapy can be performed 24 weeks after surgery.

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