Factors affecting the cure rate of kidney cancer

Generally, kidney cancer will not recur within 5 years after nephrectomy, and the 10-year survival rate is acceptable. The prognosis of kidney cancer is sometimes difficult to estimate, and metastatic lesions may appear 20, 30, or even longer after kidney cancer resection. When kidney cancer is discovered, some cases are still confined to the kidney, but a small number of cases have already metastasized to distant sites when first diagnosed. So what are the factors that affect the cure rate of kidney cancer?

Patients with renal vein invasion have long been considered to have a poor prognosis. However, in recent years, many authors have reported that renal vein invasion does not affect prognosis in patients with stage I and II tumors (without lymph node invasion).
The type of renal cell carcinoma is also related to the prognosis. Clear cell carcinoma has a lower degree of malignancy and a better prognosis; granular cell carcinoma has a higher degree of malignancy and a worse prognosis; spindle cell carcinoma has the worst differentiation and the highest degree of malignancy, often metastasizes at an early stage, and has a poor prognosis. However, there are many types of renal cell carcinoma that are mixed. In this case, the prognosis is estimated based on the most malignant type of cancer cell.