Bone metastasis of lung cancer is mostly osteolytic destruction, while small cell undifferentiated carcinoma and a few adenocarcinomas may show osteoblastic destruction. Among patients, 86% have osteolytic destruction, 7% have osteoblastic destruction, and 7% have mixed destruction. The incidence of primary lung cancer complicated by hypercalcemia is 26%. Chemotherapy Systemic chemotherapy can control the development of bone metastasis and relieve pain while treating primary lung lesions. Therefore, it can not only relieve pain, but also kill cancer cells and control their growth. In particular, the combined chemotherapy regimen based on high-dose cisplatin is more effective. In some cases, when rechecking X-rays, it was found that bone metastases disappeared and new bone cortexes were formed. Since there may be potential micrometastases in other organs of the body when lung cancer cases have bone metastases, systemic combined chemotherapy can also have a therapeutic effect on other potential metastases while treating bone metastases. At this time, fat-soluble small molecule drugs can be used, such as elemene liposome injection green chemotherapy drugs. Radiation therapy Radiotherapy can be divided into several methods such as cobalt-60 irradiation, deep x-ray machine and linear accelerator. For isolated bone metastases, after the lung lesions are controlled and stabilized by chemotherapy, high-dose, short-course radiotherapy can be given to relieve pain, kill cancer cells and control the development of lesions. About half of the patients can completely relieve pain after radiotherapy, and about 75% of the patients can significantly reduce pain. |
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