Colorectal cancer is a general term for colon cancer and rectal cancer. Colorectal cancer refers to malignant lesions of the colorectal mucosal epithelium caused by multiple carcinogenic factors such as environmental or genetic factors. It has a poor prognosis and a high mortality rate. Colorectal cancer is a malignant tumor originating from the colorectal mucosal epithelium and is one of the most common malignant tumors of the digestive tract. What are the causes of colorectal cancer? Like other malignant tumors, the cause of colorectal cancer is still unclear, but it may be related to the following factors. 1. Environmental factors Studies have shown that among various environmental factors, diet is the most important, and the incidence of colorectal cancer is positively correlated with the high fat consumption in food. In addition, it may also be related to the lack of trace elements and changes in lifestyle habits. 2. Genetic factors There are reports of "familial colorectal cancer" both at home and abroad. The number of blood relatives of colorectal cancer patients who died of the disease is significantly higher than that of the general population. Some colorectal adenomas, such as multiple familial adenomatosis, are autosomal dominant genetic diseases with a family prevalence rate of up to 50%. If not treated, there is a possibility of colorectal cancer after the age of 10. Recently, some scholars have studied the relationship between tumor suppressor genes and colorectal cancer and found that the susceptibility and pathogenesis of colorectal cancer are both related to genetic factors. 3. Colon adenoma According to the research of autopsy materials from various places, the incidence of colon adenoma is quite consistent with that of colon cancer. According to statistics, the incidence of colon cancer in patients with one adenoma is 5 times higher than that in patients without adenoma, and the incidence of colorectal cancer in patients with multiple adenomas is 1 times higher than that in patients with a single adenoma. 4. Chronic colon inflammation: It is reported that the prevalence of intestinal cancer is positively correlated with the prevalence of schistosomiasis. It is generally believed that due to schistosomiasis, inflammatory changes in the intestines may lead to cancer in some cases. Other chronic inflammations of the intestines may also lead to cancer, such as ulcerative colitis, which has a 3% to 5% chance of cancer. Traditional Chinese medicine believes that the onset of colorectal cancer is related to gastrointestinal coldness, irregular diet, and external invasion of evil. |
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